RecruitingNCT06717984

AI Model for Classifying Breast Cancer From Histopathology Images

A Study on Artificial Intelligence Algorithms for Breast Cancer Classification From Histopathology Images


Sponsor

Taufiq Hasan, PhD

Enrollment

500 participants

Start Date

Jan 11, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Breast cancer, a prevalent and potentially fatal disease, underscores the need for early and accurate detection to improve patient outcomes. Traditional histopathological examination, the current gold standard for diagnosis, faces limitations like subjectivity and low efficiency. In response, this research seeks to revolutionize breast cancer diagnostics by using deep learning techniques to classify invasive and noninvasive breast cancer types from histopathological images. Non-invasive cancers, like DCIS and LCIS, are confined to milk ducts or lobules, while invasive cancers spread to surrounding tissue and make up 70% of cases, often leading to poorer outcomes. The proposed AI model aims to enhance diagnostic accuracy and efficiency, surpassing manual methods, and providing a scalable solution for diverse healthcare settings. By automating image analysis, the model seeks to democratize cancer screening, making it accessible in underserved populations and adaptable to different resources and equipment. Ultimately, this research aims to advance breast cancer detection, improve patient care, and contribute to better treatment outcomes globally.


Eligibility

Sex: FEMALE

Plain Language Summary

Simplified for easier understanding

This study is developing an artificial intelligence (AI) tool that can analyze tissue samples from biopsies to help detect and classify breast cancer. The goal is to see if AI can assist doctors in diagnosing breast cancer more accurately and efficiently. **You may be eligible if...** - You are a female of any age - You are willing to participate in breast cancer screening - You are able to have a biopsy done - You do not currently have a breast cancer diagnosis and have never had one - Your medical records are available for the study to review **You may NOT be eligible if...** - You are currently pregnant - You have a serious medical condition that makes a tissue sample exam unsafe - You have conditions that could interfere with the accuracy of the screening results - You are coming in for a follow-up screening (only first-time screenings are included) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTBiopsy, Mastectomy, Histopathology

Biopsy: This intervention involves the collection of breast tissue samples through a biopsy procedure. These samples are obtained from women undergoing investigation for unusual cell growth and are analyzed to detect potential abnormalities, including benign, in situ, or invasive cancerous changes. Mastectomy: This intervention refers to the surgical removal of breast tissue, typically performed to treat or prevent the spread of breast cancer. It may involve the removal of part or all of the breast and is considered in cases of invasive breast cancer or high-risk noninvasive breast cancer. Histopathology: This intervention focuses on the microscopic examination of breast tissue samples collected through biopsy or mastectomy. Histopathological analysis is conducted to assess cellular abnormalities, determine the presence of cancer, and classify the tissue as benign, in situ, or invasive, providing the basis for diagnosis and treatment decisions.


Locations(1)

National Institute of Cancer Research & Hospital (NICRH)

Dhaka, Bangladesh

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NCT06717984


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