RecruitingEarly Phase 1NCT06720090

Light Therapy for Obsessive-compulsive Disorder (OCD)

Light Therapy for Obsessive-compulsive Disorder: A Circadian Medicine Approach


Sponsor

Washington University School of Medicine

Enrollment

40 participants

Start Date

Dec 16, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to test whether light therapy is effective for reducing symptoms in young adults with OCD and late bedtimes (1am or later). The main question\[s\] it aims to answer are: Does light therapy reduce OCD symptoms? Does light therapy advance the circadian clock? If there is a comparison group: Researchers will compare a higher dose of light therapy to a lower dose to see if dose amount affects symptom reduction. Participants will asked to: 1. Wear light therapy glasses for 1 hour each morning and complete a daily light therapy log for 5 weeks 2. Track their sleep every day with a wearable monitor and an electronic sleep diary for 5 weeks 3. Complete a 1-time assessment of sensitivity to light exposure 4. Complete self-report measures of OCD 4 times/day at baseline (2 weeks), mid-treatment (1 week), and end of treatment (1 week)


Eligibility

Min Age: 17 YearsMax Age: 35 Years

Inclusion Criteria4

  • Primary DSM-5 OCD diagnosis
  • Bedtime 0100 or later
  • Age 18-35
  • English speaking

Exclusion Criteria7

  • Subjects must not be currently participating in another research study that would influence their participation in our study.
  • Diagnostic status
  • Treatment status
  • Night shift work or travel more than 1 time zone outside of Central Standard Time (CST) in the past month
  • Pregnancy status
  • Medication status
  • Regular nicotine or marijuana use

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Interventions

BEHAVIORALLight therapy

5 weeks of light therapy administered via wearable light therapy glasses worn for 1 hour each morning after awakening.


Locations(1)

Washington University

St Louis, Missouri, United States

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NCT06720090


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