OCD Clinical Trials

16 recruiting

OCD Trials at a Glance

35 actively recruiting trials for ocd are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 22 trials, with the heaviest enrollment activity in Houston, New York, and Philadelphia. Lead sponsors running ocd studies include Yale University, Baylor College of Medicine, and University of Pennsylvania.

Browse ocd trials by phase

Treatments under study

About OCD Clinical Trials

Looking for clinical trials for OCD? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new OCD trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about OCD clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 35 trials

Recruiting

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Healthy VolunteerTobacco Use DisorderMigraine+7 more
Yale University200 enrolled2 locationsNCT06624137
Recruiting
Not Applicable

OCD LIFU Target Engagement

Obsessive Compulsive Disorder (OCD)
University of Pennsylvania10 enrolled1 locationNCT07558148
Recruiting

Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments

Anxiety DepressionDepressionOCD
Neuronetics12,000 enrolled1 locationNCT06997549
Recruiting

Prediction Model for Postoperative Cognitive Dysfunction in Elderly Cardiac Patients: A Special Disease Cohort Study

Cardiac Diseases Requiring SurgeryPostoperative Cognitive Dysfunction (POCD)
Shanghai Geriatric Medical Center634 enrolled1 locationNCT07483047
Recruiting
Phase 1

Open-Label Psilocybin Study in Transdiagnostic Population

AnxietyDepression - Major Depressive DisorderPTSD+5 more
Yale University50 enrolled1 locationNCT06442423
Recruiting
Not Applicable

Neurostimulation Versus Therapy for Problems With Emotions

Eating DisordersAnxiety DisordersObsessive-Compulsive Disorder+12 more
Duke University240 enrolled1 locationNCT05712057
Recruiting
Not Applicable

Stepped Care Treatment for Anxiety Resilience

Obsessive Compulsive Disorder (OCD)Specific PhobiaGeneralized Anxiety Disorder (GAD)+3 more
Andrew Wiese106 enrolled1 locationNCT07228143
Recruiting
Not Applicable

Accelerated TMS for Depression and OCD

DepressionOCD
Weill Medical College of Cornell University500 enrolled1 locationNCT04982757
Recruiting
Not Applicable

Objective Characterizatoion of Repetitive Behaviors

Tic DisordersOCDGilles de la Tourette Syndrome
Institut National de la Santé Et de la Recherche Médicale, France50 enrolled3 locationsNCT06050369
Recruiting
Not Applicable

Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder

Obsessive Compulsive Disorder (OCD)
Yale University180 enrolled1 locationNCT06834217
Recruiting
Not Applicable

Audio-Recorded Messages Delivered Via iPad to Prevent Delirium in Hip Fracture Patients

Delirium - PostoperativeDelirium and Post-operative Cognitive Dysfunction (POCD)
Sengkang General Hospital30 enrolled1 locationNCT07396532
Recruiting
Not Applicable

A Lifestyle Intervention to Reduce Cardiometabolic Risk Factors in Individuals With Obsessive-compulsive Disorder

Obsessive Compulsive Disorder (OCD)Lifestyle (Sedentary Behavior and Physical Activity)
Karolinska Institutet108 enrolled1 locationNCT07206212
Recruiting

Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder

OCD
Centre Hospitalier Henri Laborit100 enrolled1 locationNCT05843604
Recruiting
Not Applicable

Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings

AnxietyObsessive Compulsive Disorder (OCD)Social Anxiety Disorder+12 more
Bradley Hospital501 enrolled1 locationNCT06934525
Recruiting
Not Applicable

ERP to Improve Functioning in Veterans With OCD

Obsessive Compulsive Disorder (OCD)Comorbid Post-Traumatic Stress Disorder and OCD
VA Office of Research and Development160 enrolled18 locationsNCT05240924
Recruiting
Not Applicable

Paired tVNS With ERP in OCD

OCD
University of Florida56 enrolled1 locationNCT05580614
Recruiting
Not Applicable

How Hormones and Exposure and Response Prevention (EX/RP) Affect the Brain of People With OCD

OCD
University of Pennsylvania120 enrolled2 locationsNCT05359562
Recruiting
Not Applicable

Accelerated rTMS Therapeutic Approach for Refractory Obsessive-Compulsive Disorder

Obsessive Compulsive Disorder (OCD)
Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University20 enrolled1 locationNCT07198594
Recruiting
Not Applicable

Neuromodulation for a Novel OCD Biomarker and Treatment

OCD
Boston University Charles River Campus90 enrolled1 locationNCT05994053
Recruiting

Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation

Behavioral ActivationMajor Depressive DisorderAnxiety Disorders+3 more
University of Manitoba160 enrolled2 locationsNCT06763081