OCD Clinical Trials

9 recruiting

Frequently Asked Questions

Common questions about OCD clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 29 trials

Recruiting
Not Applicable

Acceptance and Commitment Therapy for Religious OCD

Obsessive Compulsive Disorder (OCD)
University of Alabama at Birmingham10 enrolled1 locationNCT06647589
Recruiting
Phase 1

Open-Label Psilocybin Study in Transdiagnostic Population

AnxietyDepression - Major Depressive DisorderPTSD+5 more
Yale University50 enrolled1 locationNCT06442423
Recruiting

LHC-CIDI-5 in Hong Kong

Suicidal IdeationObsessive Compulsive Disorder (OCD)Major Depressive Disorder (MDD)+20 more
The University of Hong Kong2,500 enrolled1 locationNCT06804525
Recruiting
Not Applicable

The Efficacy of Temporal Interference Stimulation in the Treatment of Obsessive-Compulsive Disorder

Obsessive Compulsive Disorder (OCD)
Shanghai Mental Health Center18 enrolled1 locationNCT07113652
Recruiting
Not Applicable

Neurostimulation Versus Therapy for Problems With Emotions

Eating DisordersAnxiety DisordersObsessive-Compulsive Disorder+12 more
Duke University240 enrolled1 locationNCT05712057
Recruiting
Not Applicable

Stepped Care Treatment for Anxiety Resilience

Obsessive Compulsive Disorder (OCD)Specific PhobiaGeneralized Anxiety Disorder (GAD)+3 more
Andrew Wiese106 enrolled1 locationNCT07228143
Recruiting
Not Applicable

Accelerated TMS for Depression and OCD

DepressionOCD
Weill Medical College of Cornell University500 enrolled1 locationNCT04982757
Recruiting
Not Applicable

Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder

Obsessive Compulsive Disorder (OCD)
Yale University180 enrolled1 locationNCT06834217
Recruiting
Not Applicable

A Lifestyle Intervention to Reduce Cardiometabolic Risk Factors in Individuals With Obsessive-compulsive Disorder

Obsessive Compulsive Disorder (OCD)Lifestyle (Sedentary Behavior and Physical Activity)
Karolinska Institutet108 enrolled1 locationNCT07206212
Recruiting

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

Traumatic Brain InjuryEhlers-Danlos SyndromePost-Acute COVID-19 Syndrome+41 more
Brain Inflammation Collaborative10,000 enrolled1 locationNCT04806620
Recruiting
Not Applicable

Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings

AnxietyObsessive Compulsive Disorder (OCD)Social Anxiety Disorder+12 more
Bradley Hospital501 enrolled1 locationNCT06934525
Recruiting
Not Applicable

ERP to Improve Functioning in Veterans With OCD

Obsessive Compulsive Disorder (OCD)Comorbid Post-Traumatic Stress Disorder and OCD
VA Office of Research and Development160 enrolled18 locationsNCT05240924
Recruiting
Not Applicable

DBS for Obsessive-Compulsive Disorder

Obsessive Compulsive Disorder (OCD)
Northwell Health50 enrolled1 locationNCT02773082
Recruiting
Not Applicable

Accelerated rTMS Therapeutic Approach for Refractory Obsessive-Compulsive Disorder

Obsessive Compulsive Disorder (OCD)Obsessive-Compulsive Disorder
Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University20 enrolled1 locationNCT07198594
Recruiting

Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation

Behavioral ActivationMajor Depressive DisorderAnxiety Disorders+3 more
University of Manitoba160 enrolled2 locationsNCT06763081
Recruiting
Not Applicable

Efficacy and Mechanism of Augmentation of Cognitive Behavioral Therapy With Transcranial Alternating Current Stimulation(tACS) for Obsessive-Compulsive Disorder (OCD)

Obsessive Compulsive Disorder (OCD)
Shanghai Mental Health Center62 enrolled1 locationNCT06717165
Recruiting
Not Applicable

Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD

Obsessive Compulsive Disorder (OCD)Panic DisorderGeneralized Anxiety Disorder (GAD)+6 more
Baylor College of Medicine174 enrolled1 locationNCT07024758
Recruiting
Not Applicable

Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder

Obsessive Compulsive Disorder (OCD)
Icahn School of Medicine at Mount Sinai20 enrolled1 locationNCT05160129
Recruiting

Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments

Anxiety DepressionDepressionOCD
Neuronetics12,000 enrolled1 locationNCT06997549
Recruiting
Not Applicable

Gamified Combined Cognitive Bias Modification in Adults Diagnosed With OCD: Randomized Controlled Trial

Obsessive Compulsive Disorder (OCD)
Dokuz Eylul University90 enrolled1 locationNCT06941155