Ultrasound-Guided Microwave Ablation Vs. Surgery for Low-Risk PapilaryThyroid Carcinoma

This study compares microwave ablation (a heat-based procedure to destroy tumors using a needle) versus surgery for treating small, low-risk papillary thyroid cancer, to see if ablation is equally safe and effective while being less invasive. **You may be eligible if...** - Have papillary thyroid carcinoma (a common, typically slow-growing thyroid cancer) confirmed by fine-needle aspiration biopsy - Tumor has a confirmed low-risk genetic mutation profile - Do not have serious organ failure (heart, lungs, or kidneys) **You may NOT be eligible if...** - Have a high-risk or aggressive genetic mutation in your thyroid tumor - Have already had thyroid surgery or radiation - Have cancer that has spread to lymph nodes or distant sites - Have serious heart, lung, or kidney problems Talk to your doctor to see if this trial is right for you.