RecruitingPhase 4NCT06726395

Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia

Randomized Controlled Clinical Trial Comparing Treatment With Cloxacillin Versus Benzylpenicillin in Bacteraemia Caused by Penicillin-susceptible Staphylococcus Aureus (PSSA)

Sponsor

Region Skane

Enrollment

420 participants

Start Date

Mar 10, 2025

Study Type

INTERVENTIONAL

Conditions

Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia)Staphylococcus Aureus Bacteraemia Staphylococcal Bacteraemia Staphylococcus (S.) Aureus Infection

Summary

The goal of this study is to investigate if benzylpenicillin is a better treatment option than cloxacillin in patients with penicillin-susceptible Staphylococcus aureus bacteraemia.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Penicillin G_1200mg and a drug called cloxacillin for people with staphylococcal bacteraemia, staphylococcus (s.) aureus infection, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGPenicillin G_1200mg

benzylpenicillin preferred dosing 1gx4

DRUGcloxacillin

cloxacillin 2gx4

Locations(1)

Skånes universitetssjukhus, Region Skåne

Lund, Sweden

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NCT06726395

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