Glycan Supplementation on a Human Model of Crohn's Disease Initiation and Progression

This study is testing whether a glycan (a type of dietary supplement derived from natural sugars) can help prevent Crohn's disease from coming back after bowel surgery. Researchers want to see if this supplement can change gut bacteria and reduce inflammation that leads to disease recurrence. **You may be eligible if...** - You are 18 to 75 years old - You have a confirmed diagnosis of Crohn's disease affecting the small intestine or the junction of small and large bowel - You recently had surgery to remove a diseased portion of your bowel (ileal or ileocecal resection) **You may NOT be eligible if...** - You have ulcerative colitis, indeterminate colitis, or microscopic colitis (not Crohn's) - You are on antibiotics, immunosuppressants, biologics, or other medications to prevent disease recurrence after surgery - You are pregnant, breastfeeding, or planning to become pregnant - You are allergic to shellfish or glycan products - You have a history of cancer (other than skin cancer), bleeding disorders, or poorly controlled diabetes - You are on anticoagulant therapy (blood thinners) Talk to your doctor to see if this trial is right for you.