Efficacy and Safety of DTMS in Adolescent Major Depressive Disorder

This study is testing a brain stimulation technique called Deep Transcranial Magnetic Stimulation (DTMS) in adolescents and young adults with major depression. DTMS uses magnetic pulses delivered through a helmet-like device to stimulate specific brain regions and reduce depression symptoms — without surgery or medication. **You may be eligible if...** - You are between 11 and 23 years old and right-handed - You have been diagnosed with major depressive disorder (MDD) based on DSM-5 criteria - A formal evaluation (using the MINI interview) confirmed your current depressive episode - You scored above 13 on the Beck Depression Inventory (BDI-II) - You are willing to follow the study protocol and can sign (or have a guardian sign) consent **You may NOT be eligible if...** - You have another psychiatric diagnosis - You have a significant neurological condition (brain tumor, seizures, severe head injury) - You have an active high risk of suicide or a suicide attempt in the past 6 months - You have previously received TMS, ECT, tDCS, or tACS treatment - You have metal implants or electronic devices in your body (which are incompatible with magnetic stimulation) - You participated in a drug trial in the past 6 months Talk to your doctor to see if this trial is right for you.