Prospective Study of Classification and Activity Assessment of Psoriatic Arthritis Based on Power Doppler (PD) Ultrasonography (PDUS)
A Single Centre Prospective Cohort Study of Classification and Activity Assessment of Psoriatic Arthritis Based on Power Doppler (PD) Ultrasonography (PDUS)
Nanjing Medical University
400 participants
Sep 1, 2023
OBSERVATIONAL
Conditions
Summary
Psoriatic arthritis (PsA) is a complex inflammatory disease with heterogeneous clinical features, which complicates psoriasis in 30% of patients. PsA involves multiple tissues and clinical domains including skins and nails as well as arthritis, spondylitis, enthesitis, and dactylitis. Power Doppler (PD) ultrasonography (PDUS) is a sensitive non-invasive imaging technology used to assess disease activity and treatment response in PsA. This is a prospective, observational, open-label study to investigate disease activity, therapeutic response and bone destruction based on ultrasonography findings in patients with PsA.
Eligibility
Inclusion Criteria3
- PsA patients as defined by CASPAR criteria
- Patients must be able to comply with the visit schedule, treatment plan, laboratory tests and other study procedures
- Patients must be given informed consent
Exclusion Criteria4
- History of other arthritis within the last 12 months
- Concomitant disease with acute or chronic infectious diseases
- Pregnancy or laction
- Poorly tolerated with venipuncture required for blood sampling during the study
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Locations(2)
View Full Details on ClinicalTrials.gov
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NCT06730334