RecruitingNot ApplicableNCT06736002

Effects of Mega-dose Vitamin D Pulse and Maintenance Therapy on Seizure Frequency, Fatigue, and Quality of Life: A Prospective Study


Sponsor

Chin-Wei Huang

Enrollment

200 participants

Start Date

Feb 3, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This prospective study aims to evaluate the effects of mega-dose vitamin D pulse therapy followed by maintenance therapy on seizure frequency, fatigue, and quality of life in patients with epilepsy. Participants will receive vitamin D supplementation, and clinical outcomes will be assessed over time to determine its potential benefits on seizure control and patient-reported outcomes.


Eligibility

Inclusion Criteria4

  • Aged 20 or above (inclusive)
  • Diagnosed patients (refractory epilepsy refers to those who have used more than two drugs, and each drug has reached the When epileptic seizures cannot be well controlled at standard reasonable treatment doses, it is called refractory epilepsy)
  • There is no imaging evidence of persistence or expansion of brain damage in the past three years
  • Subjects or family members (caregivers) can comply with the trial plan and take vitamin D patients

Exclusion Criteria1

  • \-

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Interventions

OTHERVitamin D

Vitamin D

OTHERPlacebo

Placebo oral solution


Locations(1)

National Cheng Kung University Hospital

Tainan, Taiwan

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NCT06736002


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