RecruitingPhase 3NCT06738251

A Phase III Study of SHR-A2102 Versus Investigator-selected Therapy in Advanced Urothelial Carcinoma

A Randomized, Open-label, Controlled, Multicenter Phase III Clinical Study of SHR-A2102 for Injection Versus Investigator-selected Therapy in Locally Advanced or Metastatic Urothelial Carcinoma Previously Treated With Platinum-Containing Chemotherapy and PD-(L)1 Inhibitors and With or Without ADC


Sponsor

Shanghai Hengrui Pharmaceutical Co., Ltd.

Enrollment

402 participants

Start Date

Feb 12, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate the efficacy and safety of SHR-A2102 for injection versus Investigator-selected Therapy in patients with Locally advanced or Metastatic Urothelial Carcinoma who have been previously treated with platinum-based chemotherapy and PD-(L)1 inhibitors.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Docetaxel Injection, a drug called Gemcitabine Hydrochloride for Injection, and others for people with advanced urothelial carcinoma. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSHR-A2102 for Injection

SHR-A2102 for Injection.

DRUGDocetaxel Injection

Docetaxel Injection.

DRUGPaclitaxel Injection

Paclitaxel Injection.

DRUGGemcitabine Hydrochloride for Injection

Gemcitabine Hydrochloride for Injection.

DRUGPemetrexed Disodium for Injection

Pemetrexed Disodium for Injection.


Locations(1)

Beijing Cancer Hospital

Beijing, Beijing Municipality, China

View Full Details on ClinicalTrials.gov

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NCT06738251


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