RecruitingNot ApplicableNCT06738849

EkiYou-Study-2 : A National Multicentric Trial of the EkiYou Application for Insulin Bolus Calculation

EkiYou-Study-2 : Multicenter Randomised Controlled Trial of the EkiYou Application for Insulin Bolus Calculation


Sponsor

DiappyMed

Enrollment

154 participants

Start Date

Nov 5, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

EkiYou-Study-2 is an interventional multicenter randomised controlled clinical investigation according to EU 2017/745. It is conducted in 154 adults with diabetes and treated by multiple daily insulin injections that will be followed for 6 months. After a randomization, participants will receive for 6 months EkiYou V2 Digital Therapy that will help them to estimate their daily bolus and basal insulin doses. This device weekly adjusts insulin parameters including : basal insulin dose, insulin to carb ratios and correction factor. The control group will stay with their standard care, and after the first three months of control period, they will receive EkiYou V2 for the last three months. The aim of this study is to examine the performance of the EkiYou V2 Digital Therapy compared with conventional methods for people with diabetes treated with multi-injections as part of a basal-bolus regimen. We also aim to assess the level of satisfaction and user experience with the EkiYou application, as well as the quality of life of study participants.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study evaluates an app called EkiYou that helps people with diabetes calculate the correct dose of fast-acting insulin before meals. The trial looks at whether this digital tool improves blood sugar control compared to standard care across multiple centers in France. **You may be eligible if...** - You are 18 or older - You have type 1 diabetes, type 2 diabetes, or diabetes caused by pancreatic disease - You have been on a multiple daily injection insulin regimen (basal and bolus insulin) for at least 6 months - You use a compatible fast-acting insulin (such as NovoRapid, Humalog, or Fiasp) and a compatible long-acting insulin (such as Lantus or Tresiba) - You use a continuous glucose monitor (CGM) **You may NOT be eligible if...** - You do not use the specific types of insulin compatible with the EkiYou device - You do not use a continuous glucose monitor - You have been on this insulin regimen for less than 6 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEEkiYou V2

Use of a Digital Therapy in the form of a mobile application that helps users to evaluate their daily bolus and basal insulin needs, and that adjusts at weekly basis their insulin to carb ratios, correction factor and basal dose. The device includes the following features to participants: * Carbohydrate counting through an extensive food database with more than 200k items. * Bolus calculation based on their meal, physical activity and blood glucose. * Bolus correction advice. * Long-acting insulin reminders and automatic periodic titration. * Insulin-to-carb ratios and correction factor automatic adjustment.


Locations(16)

APHP Avicennes

Bobigny, France

CHU CAEN

Caen, France

IDNC

Chartres, France

CHSF Corbeil-Essonnes

Corbeil-Essonnes, France

Cabinet Dr Picard

Dijon, France

GH Le Havre - Hôpital Jacques Monod

Le Havre, France

CHU Limoges - Dupuytren

Limoges, France

Fondation Ambroise Paré / HEM

Marseille, France

Cabinet Dr Navaranne

Mérignac, France

University Hospital, Montpellier

Montpellier, France

APHP - Hôpital La Pitié Salpêtrière

Paris, France

CH Périgueux

Périgueux, France

Cabinet Dr Diedisheim

Saint-Cyr-sur-Loire, France

Cabinet Dr Gervaise

Saint-Cyr-sur-Loire, France

CHU Toulouse - Hôpital Rangueil

Toulouse, France

Clinique Pasteur

Toulouse, France

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NCT06738849


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