RecruitingNCT06738888

Renovated Prediction Model for Difficult Transoral and Submental Endoscopic Thyroidectomy

A Functional-oriented Modification of TOaST Based on Partial Preservation of the Lines Alba Cervical

Sponsor

Shanghai 6th People's Hospital

Enrollment

300 participants

Start Date

May 1, 2024

Study Type

OBSERVATIONAL

Conditions

Thyroid Cancer Thyroid Diseases Thyroid Nodule

Summary

The investigators have previously proposed a prediction model for difficult transoral and submental thyroidectomy through a retrospective study. In order to better promote transoral and submental endoscopic approach for thyroid surgery and to set up an appropriate training course, the investigators aim to refine the procedure through a prospective study.

Eligibility

Plain Language Summary

Simplified for easier understanding

This study aims to build a better prediction model to identify which patients are good candidates for a minimally invasive thyroid surgery done through the mouth or under the chin (transoral or submental endoscopic thyroidectomy), avoiding a visible scar on the neck. **You may be eligible if...** - You have a confirmed diagnosis of differentiated thyroid cancer with a tumor no larger than 4 cm - You have a benign (non-cancerous) thyroid nodule no larger than 6 cm - There is no sign of cancer spread to nearby lymph nodes or distant organs **You may NOT be eligible if...** - Your lymph nodes in the neck are fused or fixed - You have had previous neck surgery or neck radiation - Your vocal cords are not moving properly before surgery - Your thyroid nodule is suspicious for a specific aggressive cancer type (tall cell papillary thyroid cancer) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREModified TOaST with caudal linea alba preservation

The modified procedure consists of cranial limited opening of the linea alba cervicalis with intentional preservation of the caudal linea alba-strap muscle fascial bridge. Bilateral symmetric suspension of the strap muscles is performed to maintain a centered operative window for thyroid lobectomy and, when indicated, ipsilateral central compartment lymph node dissection. If exposure is inadequate, the caudal linea alba may be further opened for safety.