Thyroid Nodule Clinical Trials

20 recruiting

Frequently Asked Questions

Common questions about Thyroid Nodule clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 32 trials

Recruiting
Not Applicable

The Outcomes of Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules

Thyroid Nodules
Chinese PLA General Hospital1,500 enrolled1 locationNCT06340945
Recruiting

Postoperative Hypocalcemia After Thyroidectomy

Thyroid CancerPostoperative ComplicationsThyroid Nodule+2 more
Minia University600 enrolled1 locationNCT07428057
Recruiting
Not Applicable

Active Surveillance for Bethesda IV Thyroid Nodules

Thyroid CancerThyroid Nodule
Christian Grønhøj Larsen165 enrolled1 locationNCT07370675
Recruiting
Not Applicable

Thyroid Artery Embolization for the Treatment of Compressive Goiters.

Thyroid Nodules
Université de Sherbrooke20 enrolled1 locationNCT07360587
Recruiting
Not Applicable

Thyroid Artery Goitre Embolization Trial A Pilot Study Investigating Thyroid Artery Embolisation as a Treatment for Large Thyroid Nodules

Graves DiseaseThyroid Nodule \(Benign\)Goitre
Royal Berkshire NHS Foundation Trust10 enrolled1 locationNCT07046546
Recruiting
Not Applicable

Prospective Evaluation of the Pulse Biosciences nPulse™ Vybrance™ Percutaneous Electrode System

AblationThyroid NoduleThyroid Goiter
Pulse Biosciences, Inc.100 enrolled2 locationsNCT07287176
Recruiting
Not Applicable

Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures

Thyroid NodulesInferior Turbinate HypertrophyChronic Rhinosinusitis (CRS)+2 more
Cedars-Sinai Medical Center184 enrolled1 locationNCT07299474
Recruiting
Not Applicable

A Study of Multiparametric Ultrasound Imaging Methods

Pancreatic CancerThyroid Nodule
Memorial Sloan Kettering Cancer Center85 enrolled7 locationsNCT07270237
Recruiting
Not Applicable

Decision Aid and Thyroid Nodules Management

Thyroid Nodule
Stony Brook University134 enrolled1 locationNCT05264857
Recruiting
Not Applicable

Radiofrequency Ablation Study in LatinX Patients

Thyroid Nodule
Northwell Health44 enrolled1 locationNCT05903196
Recruiting
Not Applicable

Ultrasound and Cytological Evaluation 3 Years After Radiofrequency Thermal Ablation of Benign Thyroid Nodules : a Prospective Exploratory Cohort of 180 Nodules

Thyroid NodulesThermal AblationFine Needle Aspiration Biopsy
Assistance Publique - Hôpitaux de Paris180 enrolled1 locationNCT05726981
Recruiting
Not Applicable

TRAIL Study: Feasibility and Pilot

Thyroid CancerThyroid NoduleThyroid Neoplasms
Dartmouth-Hitchcock Medical Center20 enrolled1 locationNCT06220656
Recruiting
Not Applicable

Safety & Feasibility of Ultrasound-assisted Non-invasive Measurement of Compressibility of the Thyroid Gland in Patients Scheduled for Surgical Removal

Thyroid Nodule (Diagnosis)
Insel Gruppe AG, University Hospital Bern30 enrolled1 locationNCT07102264
Recruiting

RFA of Benign Thyroid Nodules: Clinical Outcomes and Quality of Life Study

Thyroid Nodules
Columbia University100 enrolled1 locationNCT05189314
Recruiting
Not Applicable

The Safety and Feasibility of Radiofrequency Ablation to Treat Low-risk Thyroid Cancer

Thyroid CancerThyroid Nodule
University Health Network, Toronto40 enrolled1 locationNCT06929650
Recruiting

Ultrasound-guided Thermal Ablation for Bethesda III/IV Thyroid Nodules

Thyroid Nodule
Chinese PLA General Hospital600 enrolled2 locationsNCT06733753
Recruiting

Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules

Thyroid Nodule \(Benign\)
Chinese PLA General Hospital1,500 enrolled1 locationNCT06729762
Recruiting

Renovated Prediction Model for Difficult Transoral and Submental Endoscopic Thyroidectomy

Thyroid CancerThyroid DiseasesThyroid Nodule
Shanghai 6th People's Hospital300 enrolled1 locationNCT06738888
Recruiting

Evaluation of Different Diagnostic Therapeutic Strategies in Patients with Thyroid Pathology

Thyroid CarcinomaHypothyroidismThyroid Nodule \(Benign\)+1 more
IRCCS Azienda Ospedaliero-Universitaria di Bologna5,850 enrolled1 locationNCT06779747
Recruiting
Not Applicable

Myo-inositol and Selenium in Indeterminate Thyroid Nodules (TIR3a)

Thyroid Nodule
Regina Elena Cancer Institute30 enrolled1 locationNCT06736015