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RecruitingNot ApplicableNCT06742450

Constant Current Versus Constant Voltage Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson's Disease

Prospective Study of Constant Current Versus Constant Voltage Deep Brain Stimulation in Patients with Parkinson's Disease

Sponsor

Xuanwu Hospital, Beijing

Enrollment

180 participants

Start Date

Jan 27, 2024

Study Type

INTERVENTIONAL

Conditions

Parkinson's Disease (PD)

Summary

To compare the efficacy, programming burden, power consumption, and physicians' and patients' satisfaction between current mode and voltage mode of deep brain stimulation in each period one year after surgery.

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study compares two types of deep brain stimulation (DBS) — a brain implant that delivers electrical pulses — for people with Parkinson's disease. One type delivers constant current and the other delivers constant voltage, and researchers want to see which works better. **You may be eligible if...** - You have been diagnosed with idiopathic (typical) Parkinson's disease - You are between 18 and 75 years old - You have already had deep brain stimulation devices implanted in both sides of the brain (subthalamic nucleus), but they have not yet been turned on **You may NOT be eligible if...** - You have dementia or mental illness - You are pregnant, breastfeeding, or unable to use contraception - You have serious health conditions like cancer, severe liver or kidney disease - You have epilepsy or other seizure disorders - Your DBS electrode placement is significantly off-target - You are unable to give informed consent or cooperate with follow-up Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERConstant current (CC) subthalamic nucleus deep brain stimulation

For subjects who have decided to undergo STN-DBS surgery and meet the inclusion criteria, the constant current (CC) mode is selected as the original electronic modality one week after surgery. Regardless of any changes in programming parameters over the following year, the constant current (CC) mode will be maintained.

OTHERConstant voltage (CV) subthalamic nucleus deep brain stimulation

For subjects who have decided to undergo STN-DBS surgery and meet the inclusion criteria, the constant voltage (CV) mode is selected as the original electronic modality one week after surgery. Regardless of any changes in programming parameters over the following year, the constant voltage (CV) mode will be maintained.

Locations(1)

Xuanwu Hospital of Capital Medical University

Beijing, China

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NCT06742450

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