The Effect of Coenzyme Q10 in Preventing Pain After Thoracoscopic Surgery
The Effect of Coenzyme Q10 in Preventing Pain After Thoracoscopic Surgery: a Randomized Controlled Trial
The Second Affiliated Hospital of Chongqing Medical University
264 participants
Jan 9, 2025
INTERVENTIONAL
Conditions
Summary
This study aimed to assess the effectiveness of Coenzyme Q10 in preventing both acute and chronic pain following thoracoscopic surgery, with a focus on its potential benefits in reducing the incidence and severity of pain.
Eligibility
Inclusion Criteria5
- Aged 18-75 years;
- American Society of Anesthesiology (ASA) physical status classification I-III;
- Scheduled for elective lung resection surgery under thoracoscopy;
- Voluntarily opting for patient-controlled intravenous analgesia;
- Willing to participate in this trial after consultation with the patient or their family and signing the informed consent form.
Exclusion Criteria9
- History of previous thoracotomy or thoracoscopic surgery;
- Patients converted to open thoracotomy intraoperatively;
- Severe hepatic or renal dysfunction;
- History of substance abuse;
- Pregnancy or breastfeeding;
- History of chronic pain;
- Use of coenzyme Q10 for more than one month;
- Allergy to coenzyme Q10;
- Patients unable to communicate or cooperate.
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Interventions
Coenzyme Q10 was administered from admission to one month after discharge at a dose of 200 mg per day (200 mg/qd).
The placebo was administered from hospital admission until one month after discharge.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06743802