Hop Compounds on the Immune System in Overweight People
Effect of Iso-alpha Acids and Xanthohumol on the Human Immune System in Overweight People With the Onset of Metabolic Diseases
University of Vienna
24 participants
Feb 1, 2024
INTERVENTIONAL
Conditions
Summary
The aim of the present study is to determine the effect of Iso-alpha Acids and Xanthohumol from hops on the immune response in overweight participants.
Eligibility
Inclusion Criteria5
- BMI 25 - 29,9 kg/m²
- as well as one or more of the following incipient metabolic diseases:
- pre-diabetes (fasting blood glucose 100-125 mg/dL),
- fatty liver (grade 1-3),
- high-normal blood pressure to mild hypertension (grade 1, systolic 140-159 mmHg)
Exclusion Criteria10
- History of diseases that could falsify the study results
- inflammatory bowel diseases
- malignant diseases of the gastrointestinal tract
- food allergies
- malabsorption
- kidney or liver disease (except simple fatty liver)
- symptomatic heart failure
- Taking medication to treat these diseases
- Consumption of special diets (e.g. vegan, gluten-free)
- Pregnancy
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Interventions
Participants receive a study drink supplemented with Xanthohumol (0 mg = Placebo or 0.75 mg soluble Xanthohumol)
Participants receive a study drink supplemented with Iso-alpha Acids (0 mg = Placebo or 45 mg Iso-alpha Acids)
Participants receive a study drink supplemented with Xanthohumol and Iso-alpha Acids (0 mg = Placebo or 0.75 mg + 45 mg soluble Xanthohumol + Iso-alpha Acids)
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06745102