RecruitingNot ApplicableNCT06746168

BLOCK-study: Better Local Orthopedic Pain Control After Knee Arthroplasty

Infiltration of Local Anesthetics Between the Popliteal Artery and Capsule of the Knee (iPACK) With Femoral Triangle Block (TFB) Versus Surgical Local Infiltration Analgesia (LIA) in Unilateral Total Knee Arthroplasty (TKA): A Multicenter Double-blind, Prospective Randomized Controlled Study.

Sponsor

Jessa Hospital

Enrollment

210 participants

Start Date

Jan 9, 2025

Study Type

INTERVENTIONAL

Conditions

Knee Arthroplasty, Total

Summary

The goal of this study is to compare the anesthetic combination iPACK with femoral triangle block versus surgical LIA for unilateral TKA. We hypothesize that an iPACK block with femoral triangle block is non-inferior to surgical LIA. Furthermore, due to visualization of the relevant neural and vascular structures, the risk of accidental popliteal block, nerve damage or LAST with (a blindly performed) LIA could theoretically be reduced.

Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study compares two pain control methods used during and after total knee replacement surgery: a combination of two nerve blocks (iPACK and femoral triangle block, guided by ultrasound) versus a technique where the surgeon directly injects local anesthetic into the joint area (local infiltration analgesia, or LIA). The goal is to determine whether the ultrasound-guided nerve blocks work just as well as LIA at controlling pain, while potentially being safer. Adults scheduled for a single knee replacement with a BMI between 17 and 35 who are otherwise healthy enough for spinal anesthesia may be eligible. Participation involves being randomly assigned to one of the two pain management approaches and completing standard post-surgical recovery and pain assessment. This summary was generated with AI assistance and is intended to help patients understand the study in plain language.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURELocoregional anesthesia

The FTB + iPACK group will receive 12 ml 0,5% ropivacaine for the FTB and 20 ml of ropivacaine 0.5% for the iPACK block under US guidance after spinal anesthesia

PROCEDURELocal Anesthetic Ropivacaine

The control group (LIA) will receive 120 ml 0.25% ropivacaine for surgical LIA placement.

Locations(1)

Jessa Hospital

Hasselt, Limburg, Belgium

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NCT06746168

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