Safety and Tolerability of Vertebral Bone Marrow-derived Mesenchymal Stem Cells (BM-MSC) in Real World Scenarios of Patients With Chronic Kidney Disease (CKD)

This study tests whether injections of mesenchymal stem cells derived from vertebral bone marrow are safe and can help slow the progression of chronic kidney disease (CKD) in people whose kidneys are gradually losing function. **You may be eligible if...** - You are over 18 years old - You have chronic kidney disease (eGFR below 60 mL/min/1.73m²) - If you are a kidney transplant recipient, your kidney function has been declining for at least 6 months - If you have diabetes, your HbA1c is 9% or below **You may NOT be eligible if...** - You are severely anemic (hemoglobin below 8.5 g/dL) - You weigh more than 150 kg or have a BMI over 50 - Your blood pressure is severely uncontrolled despite multiple medications - You are currently on dialysis (hemodialysis or peritoneal) - You have had a recent heart attack, severe heart failure, or stroke within 3 months - You have liver cirrhosis, severe lung disease, or a history of recurring blood clots - You have had a solid organ transplant other than a kidney Talk to your doctor to see if this trial is right for you.