RecruitingPhase 2NCT06753565

L-carnitine Supplementation in Rheumatoid Arthritis Patients

Effect of L-carnitine Supplementation on Disease Activity in Rheumatoid Arthritis Patients


Sponsor

German University in Cairo

Enrollment

60 participants

Start Date

Dec 31, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to evaluate the effect of l-carnitine as add- on therapy for improving the outcome in rheumatoid arthritis patients.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study investigates whether L-carnitine supplementation — a naturally occurring nutrient involved in energy metabolism — can reduce inflammation and improve outcomes in people with active rheumatoid arthritis (RA) who are already on standard disease-modifying drugs. **You may be eligible if...** - You are 18–60 years old - You have been diagnosed with rheumatoid arthritis for at least 6 months - You are currently on conventional RA drugs (DMARDs) at a stable dose for at least 1 month, but your disease is still active **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have liver or kidney dysfunction above specified levels - You have an active infection or concurrent cancer - You have other uncontrolled medical conditions or other rheumatic diseases - You are taking warfarin (a blood thinner) or other drugs that interact with carnitine Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGCarnitine

It is a nutritional supplement with trade name " Carnitol®" in Egypt.

DRUGDisease-modifying anti-rheumatic drugs

They are immunosuppressive drugs used to improve disease activity in Rheumatoid Arthritis patients . Conventional DMARDs include methotrexate (Imutrexate®) , leflunomide(Arthfree®) , hydroxychloroquine (plaquenil®) and sulfasalazine(colosalazine®) .


Locations(1)

Demerdash hospital

Cairo, Demerdash, Egypt

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06753565


Related Trials