Rheumatoid Arthritis (RA) Clinical Trials

51 recruiting

Rheumatoid Arthritis (RA) Trials at a Glance

53 actively recruiting trials for rheumatoid arthritis (ra) are listed on ClinicalTrialsFinder across 6 cities in 30 countries. The largest study group is Phase 1 with 14 trials, with the heaviest enrollment activity in Beijing, Wuhan, and Sofia. Lead sponsors running rheumatoid arthritis (ra) studies include Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, University of Bonn, and Ancilia Biosciences.

Browse rheumatoid arthritis (ra) trials by phase

Treatments under study

About Rheumatoid Arthritis (RA) Clinical Trials

Looking for clinical trials for Rheumatoid Arthritis (RA)? There are currently 51 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Rheumatoid Arthritis (RA) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Rheumatoid Arthritis (RA) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 53 trials

Recruiting

Prospective Validation of a Pharmacological Biomarker for Low-Dose Rituximab in Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
University Hospital, Tours30 enrolled1 locationNCT06933134
Recruiting

Oxidative Stress in Autoimmune Rheumatic Diseases

Psoriatic Arthritis (PsA)Ankylosing Spondylitis (AS)Rheumatoid Arthritis (RA)+1 more
University of Thessaly200 enrolled1 locationNCT07536529
Recruiting
Phase 1

A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis

HealthyRheumatoid Arthritis (RA)
Eli Lilly and Company134 enrolled9 locationsNCT07258849
Recruiting

A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic

Rheumatoid Arthritis (RA)Hidradenitis Suppurativa (HS)
Sonoma Biotherapeutics, Inc.36 enrolled10 locationsNCT07123038
Recruiting
Phase 4

Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases

Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)+9 more
University of Sao Paulo General Hospital477 enrolled2 locationsNCT07087912
Recruiting
Not Applicable

Ketogenic and Carnivore (Lion) Diets for Inflammatory Bowel Disease and Rheumatoid Arthritis

Ulcerative Colitis (UC)Rheumatoid Arthritis (RA)Crohn's Disease (CD)
Fuller Research Foundation160 enrolled1 locationNCT07524244
Recruiting
Phase 4

Oral Versus Intramuscular Steroid Use to Control Rheumatoid Arthritis Flares

Rheumatoid Arthritis (RA)
Sunnybrook Health Sciences Centre220 enrolled5 locationsNCT07245732
Recruiting
Phase 1Phase 2

Controlling Hyperactive Immunity With Long-lived Lymphocytes

Rheumatoid Arthritis (RA)Autoimmune Rheumatologic DiseaseDiffuse Cutaneous Systemic Sclerosis+1 more
Quell Therapeutics Limited16 enrolled6 locationsNCT07473154
Recruiting
Not Applicable

Dose Response of Exercise for Arthritis Management

ArthritisGoutRheumatoid Arthritis (RA)+3 more
University of South Carolina285 enrolled1 locationNCT06880653
Recruiting

Japan Post-Marketing Surveillance for Peficitinib to Assess Safety and Effectiveness in the Patients With Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
Astellas Pharma Inc3,000 enrolled47 locationsNCT03971253
Recruiting
Phase 1Phase 2

A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease

Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD)
Novartis Pharmaceuticals27 enrolled11 locationsNCT07048197
Recruiting
Phase 1

A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Autoimmune Rheumatic Diseases

Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)
Sanofi62 enrolled8 locationsNCT06647069
Recruiting
Not Applicable

Plant-Based Diet for Patients With Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
Center for Clinical Research and Prevention180 enrolled2 locationsNCT07268326
Recruiting

Clinical Cohort Construction and Therapeutic Effect Evaluation of Integrated Traditional Chinese and Western Medicine in the Treatment of Rheumatoid Arthritis

Rheumatoid Arthritis (RA)Rheumatoid Arthritis-Associated Interstitial Lung DiseaseDifficult-to-Treat Rheumatoid Arthritis
Yuanyuan Zhang10,000 enrolled1 locationNCT07484243
Recruiting
Phase 1

A First-in-human Study of KT501 Administered Subcutaneously to Patients With Rheumatoid Arthritis (RA).

Rheumatoid Arthritis (RA)
Kali Therapeutics, Inc.24 enrolled1 locationNCT07234773
Recruiting

A RWS of SC MTX in Chinese RA Patients

Rheumatoid Arthritis (RA)
Peking University People's Hospital10,000 enrolled1 locationNCT07463937
Recruiting
Not Applicable

HiSCs in the Treatment of Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
Shanghai Changzheng Hospital15 enrolled1 locationNCT06947746
Recruiting
Not Applicable

Effect of Mediterranean vs Paleolithic Diet on RA Activity, Sarcopenia and QOL: 12-Week RCT

Rheumatoid Arthritis (RA)
Kasr El Aini Hospital75 enrolled1 locationNCT07438652
Recruiting
Phase 2

Safety and Efficacy of TollB-001 Tablets in Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
Toll Biotech Co. Ltd. (Beijing)24 enrolled6 locationsNCT07408024
Recruiting
Not Applicable

At-home Ultrasound Localized Therapy for Rheumatoid Arthritis Study [At-home ULTRA Study]

Rheumatoid Arthritis (RA)
SecondWave Systems Inc.60 enrolled5 locationsNCT07163221