Rheumatoid Arthritis (RA) Clinical Trials

72 recruitingLast updated: June 18, 2026

There are 72 actively recruiting rheumatoid arthritis (ra) clinical trials across 31 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 4, Early Phase 1, Phase 3. Top locations include Beijing, Beijing Municipality, China, Wuhan, Hubei, China, Miami, Florida, United States. Updated daily from ClinicalTrials.gov.


Rheumatoid Arthritis (RA) Trials at a Glance

72 actively recruiting trials for rheumatoid arthritis (ra) are listed on ClinicalTrialsFinder across 6 cities in 31 countries. The largest study group is Not Applicable with 17 trials, with the heaviest enrollment activity in Beijing, Wuhan, and Miami. Lead sponsors running rheumatoid arthritis (ra) studies include Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Horus University, and University of Bonn.

Browse rheumatoid arthritis (ra) trials by phase

Treatments under study

About Rheumatoid Arthritis (RA) Clinical Trials

Looking for clinical trials for Rheumatoid Arthritis (RA)? There are currently 71 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Rheumatoid Arthritis (RA) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Rheumatoid Arthritis (RA) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 72 trials

Recruiting
Not Applicable

At-home Ultrasound Localized Therapy for Rheumatoid Arthritis Study [At-home ULTRA Study]

Rheumatoid Arthritis (RA)
SecondWave Systems Inc.60 enrolled5 locationsNCT07163221
Recruiting
Not Applicable

Gluten-Free vs Mediterranean Diet in Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
Hasan Kalyoncu University66 enrolled1 locationNCT07646262
Recruiting

Dysphagia in Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
Tanta University137 enrolled2 locationsNCT07401732
Recruiting

An Investigation of the Effect of Smartphone Usage Levels on Cervical Posture, Tongue Pressure, Balance, and Neck Disability in Individuals With Rheumatoid Arthritis and Ankylosing Spondylitis

Ankylosing Spondylitis (AS)Rheumatoid Arthritis (RA)Forward Head Posture
Merve Şahin111 enrolled1 locationNCT07627542
Recruiting
Phase 2

Effect of Roflumilast as Add-On Therapy in Rheumatoid Arthritis

Rheumatoid ArthritisRheumatoid Arthritis (RA)
Horus University50 enrolled1 locationNCT07632846
Recruiting
Phase 2

Desloratadine as Adjunct Therapy for Rheumatoid Arthritis

Rheumatoid ArthritisRheumatoid Arthritis (RA)
Horus University60 enrolled1 locationNCT07632872
Recruiting
Phase 1

Study of S-4321 in Participants With an Autoimmune or Immune-mediated Disease

Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Psoriasis (PsO)+3 more
Seismic Therapeutic AU Pty Ltd24 enrolled2 locationsNCT07455578
Recruiting
Phase 1Phase 2

A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease

Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD)
Novartis Pharmaceuticals27 enrolled12 locationsNCT07048197
Recruiting
Phase 1

A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Autoimmune Rheumatic Diseases

Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)
Sanofi62 enrolled7 locationsNCT06647069
Recruiting
Phase 4

Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in Inflammatory Rheumatic Disease (PREVENER)

Psoriatic Arthritis (PsA)AtherosclerosisRheumatoid Arthritis (RA)+4 more
Instituto de Investigación Marqués de Valdecilla1,944 enrolled17 locationsNCT07611747
Recruiting
Phase 1

A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
Eli Lilly and Company141 enrolled10 locationsNCT07258849
Recruiting
Phase 2

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

SclerodermaRheumatoid Arthritis (RA)Sjogren Syndrome+6 more
Artiva Biotherapeutics, Inc.90 enrolled52 locationsNCT06991114
Recruiting
Phase 1

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
Cullinan Therapeutics Inc.37 enrolled3 locationsNCT06994143
Recruiting
Phase 1Phase 2

Controlling Hyperactive Immunity With Long-lived Lymphocytes

Rheumatoid Arthritis (RA)Autoimmune Rheumatologic DiseaseDiffuse Cutaneous Systemic Sclerosis+1 more
Quell Therapeutics Limited16 enrolled6 locationsNCT07473154
Recruiting

Japan Post-Marketing Surveillance for Peficitinib to Assess Safety and Effectiveness in the Patients With Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
Astellas Pharma Inc3,000 enrolled47 locationsNCT03971253
Recruiting

Prospective Validation of a Pharmacological Biomarker for Low-Dose Rituximab in Rheumatoid Arthritis

Rheumatoid Arthritis (RA)
University Hospital, Tours30 enrolled1 locationNCT06933134
Recruiting
Phase 1

Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases

Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)Neuromyelitis Optica Spectrum Disorder (NMOSD)+6 more
Polina Stepensky120 enrolled1 locationNCT07085676
Recruiting

Oxidative Stress in Autoimmune Rheumatic Diseases

Psoriatic Arthritis (PsA)Ankylosing Spondylitis (AS)Rheumatoid Arthritis (RA)+1 more
University of Thessaly200 enrolled1 locationNCT07536529
Recruiting

A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic

Rheumatoid Arthritis (RA)Hidradenitis Suppurativa (HS)
Sonoma Biotherapeutics, Inc.36 enrolled10 locationsNCT07123038
Recruiting
Phase 4

Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases

Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)+9 more
University of Sao Paulo General Hospital477 enrolled2 locationsNCT07087912