RecruitingPhase 2NCT06758375

Low Dose Teclistamab in Newly Diagnosed Multiple Myeloma Patients

Low-dose Teclistamab As Consolidation in the First-line Treatment of Patients with Newly Diagnosed Multiple Myeloma.


Sponsor

Hospital Universitario Dr. Jose E. Gonzalez

Enrollment

10 participants

Start Date

Mar 3, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This single-arm, open-label study aims to determine the efficacy and safety of low-dose, limited-duration teclistamab as a consolidation scheme in newly diagnosed multiple myeloma (NDMM) patients.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a low dose of teclistamab — a drug that helps the immune system find and destroy multiple myeloma cancer cells — can be used safely in people who have just been diagnosed with multiple myeloma and have not yet received any treatment. **You may be eligible if...** - You are 18 or older - You have been newly diagnosed with multiple myeloma and have not yet been treated - You are in generally good health (ECOG score 0 or 1) - You agree to use reliable contraception during treatment **You may NOT be eligible if...** - You have ever received treatment for multiple myeloma before - Your cancer has spread to the brain or spinal fluid - You have another blood cancer or certain rare plasma cell disorders - You have an active or severe infection - You need supplemental oxygen due to lung disease - You have active hepatitis B, hepatitis C, or HIV - You have had a stroke or seizure in the past 6 months - You have severe heart failure Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGLow-dose teclistamab

NDMM patients will receive VRd 3x cicles followed by low dose teclistamab.


Locations(1)

Hospital Universitario Dr. Jose E. Gonzalez

Monterrey, Nuevo León, Mexico

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NCT06758375


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