RecruitingPhase 1Phase 2NCT06758544

A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Resectable Pancreatic Cancer


Sponsor

Guangdong Provincial People's Hospital

Enrollment

18 participants

Start Date

Mar 17, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is a single-center, single-arm, open investigator-initiated clinical study to evaluate the efficacy and safety of VRT106 in combination with chemotherapy in the treatment of resectable pancreatic cancer.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a drug called VRT106 combined with chemotherapy is safe and effective as a treatment for people with pancreatic cancer that is still removable by surgery. **You may be eligible if...** - You are between 18 and 75 years old - You have been diagnosed with pancreatic cancer that can be surgically removed - You are in good health (ECOG score 0 or 1) with adequate organ function - Your expected survival is at least 6 months **You may NOT be eligible if...** - You have previously received treatment for pancreatic cancer (including other oncolytic virus therapies) - You have had an organ or stem cell transplant - You have a weakened immune system - You have a known drug or alcohol dependency - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGOncolytic virus VRT106

VRT106, IV

DRUGChemotherapy

21 days/cycle, administered up to 6 cycles


Locations(1)

Guangdong Provincial People's Hospital

Guangzhou, Guangdong, China

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NCT06758544


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