RecruitingNot ApplicableNCT06758817

The Triad of Nutrition, Intestinal Microbiota and Rheumatoid Arthritis (TASTY)


Sponsor

Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa

Enrollment

100 participants

Start Date

Jan 2, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The main goal of this trial is to investigate whether a dietary intervention based on a typical Mediterranean Diet enriched with fermented foods (MedDiet+) can impact gut microbiota and RA-related outcomes.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study (TASTY) is investigating whether following a Mediterranean diet can improve gut health and reduce disease activity in people with rheumatoid arthritis (RA), a condition where the immune system attacks the joints causing pain and inflammation. **You may be eligible if...** - You have been diagnosed with rheumatoid arthritis - You are over 18 with at least 1 year of disease history - Your disease is currently active - Your medications have been stable for 12 weeks - You currently have a low to moderate adherence to a Mediterranean diet **You may NOT be eligible if...** - You are on a high dose of prednisone (7.5 mg/day or more) - You have taken antibiotics in the past 4 weeks - You have inflammatory bowel disease, celiac disease, or chronic diarrhea - You have diabetes, another immune-related disease, or major organ dysfunction - You have been diagnosed with cancer in the past 5 years - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERMedDiet+ intervention

Study arm will consume a Mediterranean like style diet enriched in fermented foods for 12 weeks

OTHERGeneral dietary recommendations

Study arm will be given general healthy eating advice at baseline.


Locations(2)

Unidade Local de Saude de Santa Maria

Lisbon, Portugal, Portugal

Faculdade Medicina de Lisboa

Lisbon, Portugal, Portugal

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NCT06758817


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