Comparison of Safety and Efficacy for Different Sedation Regimens During Colonoscopy
Evaluation of Safety and Efficacy of Non-anesthesia Provider-administered Different Anesthetic Regimens During Colonoscopy. Asingle Center, Prospective Double Blind, Randomized Study
Qassim Health Cluster
157 participants
Jun 15, 2025
INTERVENTIONAL
Conditions
Summary
This is a randomized, double-blinded, prospective study which will be conducted at the Department of Gastroenterology, King Saud Hospital, Unaizah, Qassim, Saudi Arabia. This study aims to compare safety and efficacy of different types of sedation medications for elective colonoscopy. Colonoscopy is a procedure to examine and visualize the colon by a fiberoptic tube called colonoscope. Sedation helps one to relax to avoid feel any discomfort or pain during the procedure.
Eligibility
Inclusion Criteria5
- Adults aged 18-60 years
- Both Genders
- Indication of colonoscopy procedure without advanced intervention
- American Society of Anesthesiologists (ASA) physical status I or II
- Competent to give informed consent
Exclusion Criteria8
- Personal history of allergic reaction or other contra-indications to midazolam, propofol or fentanyl
- Age below 18 or above 60 years
- Chronic use of benzodiazepines
- ASA physical status III or above
- Pregnancy
- History of smoking or alcohol abuse
- Body mass index \> 35 kg/m2
- History of airway obstruction or difficult intubation
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
It will not be used alone but in combination with Fentanyl in the Midazolam + Fentanyl group.
It will used alone in Propofol group and in combination with Fentanyl in the Propofol + Fentanyl group.
Fentanyl will not be used in isolation but will be used in combination with either Midazolam or Propofol in Midazolam + Fentanyl group and Propofol + Fentanyl group, respectively.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06763705