RecruitingNot ApplicableNCT06768424

Comparison of MIST With PRF and GBT With PRF in the Treatment of Intrabony Periodontal Defect. A Prospective RCT

Comparison of Minimally Invasive Surgical Therapy in Combination With Platelet Rich Fibrine and Guided Biofilm Therapy Combined With Platelet Rich Fibrine in the Treatment of Solitaire Intrabony Periodontal Defect A Prospective RCT.


Sponsor

Semmelweis University

Enrollment

36 participants

Start Date

Dec 20, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The aim is to evaluate in a prospective, randomized, controlled clinical study the healing of a MIST procedure combined with PRF, or GBT combined with PRF. Clinical, radiological evaluation of the regenerative surgical method and the GBT non-surgical therapy in solitaire deep intrabony periodontal defect.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria1

  • solitaire intrabony periodontal defect at least 4 mm

Exclusion Criteria6

  • Periodontitis with intrabony defect (Intrabony component ≥ 4mm, defect radiological angulation > 25°,
  • The patient is able to comply with the study -related procedures (i.e. good level of oral hygiene, follow-up procedures).
  • Patients must not be heavy smokers (<5 cigarettes/day).
  • furcation involvement
  • Full mouth plaque and bleeding scores (FMPS and FMBS) of <15% (O'Leary et al. 1972).
  • The patient is able to fully understand the nature of the study, signed informed consent.

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Interventions

DEVICEGuided biofilm therapy

Use of Airflow Plus powder subgingivally on teeth with deep periodeontal pockets

PROCEDUREPlatelet Rich Fibrin

Pack Platelet Rich Fibrin chops into the intrabony periodontla defect

PROCEDUREMinimally Invasive Surgical Technique

Periodontal intrabony defect is treated by minimally invasive surgical intervention


Locations(1)

Semmelweis University Department of Periodontology

Budapest, Budapest, Hungary

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NCT06768424


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