IBI343 Combined With Chemotherapy in Advanced Pancreatic Cancer

This study is testing a combination of IBI343 (a new antibody drug) with chemotherapy as a treatment for advanced pancreatic cancer that cannot be surgically removed or has spread to other parts of the body. **You may be eligible if...** - You have confirmed advanced, unresectable, or metastatic pancreatic adenocarcinoma (a common type of pancreatic cancer) - You are not eligible for surgery or curative radiotherapy - You have measurable disease on imaging - Your general health and organ function are adequate **You may NOT be eligible if...** - You are currently enrolled in another interventional clinical trial - You received other anti-tumor therapy recently (within 2 weeks or 5 half-lives) - You have received strong CYP3A4 inhibitor medications within 2 weeks - You have severe or uncontrolled infections - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.