RecruitingPhase 1NCT06771479

A Study Evaluating the Safety and Immunogenicity of MVA Strain Monkeypox Attenuated Live Vaccine

A Randomized, Double-blind, Placebo-controlled Phase I Clinical Trial Evaluating the Safety and Immunogenicity of MVA Strain Monkeypox Attenuated Live Vaccine for Individuals Aged 18 and Above


Sponsor

Shanghai Institute Of Biological Products

Enrollment

120 participants

Start Date

Jan 22, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is a randomized, double blinded, controlled phase I clinical study. To evaluate the safety and immunogenicity of receiving two doses of MVA strain monkeypox attenuated live vaccine in individuals aged 18 years and above.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called MVA strain monkeypox attenuated live vaccine (high dose), a biological treatment called MVA strain monkeypox attenuated live vaccine (low dose), and others for people with monkeypox. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALMVA strain monkeypox attenuated live vaccine (low dose)

Low dose MVA strain monkeypox attenuated live vaccine

BIOLOGICALMVA strain monkeypox attenuated live vaccine (high dose)

High dose MVA strain monkeypox attenuated live vaccine

OTHERPlacebo

Vaccine excipient


Locations(1)

Henan Infectious Disease Hospital

Zhengzhou, Henan, China

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NCT06771479


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