RecruitingNot ApplicableNCT06773299

Enhancing Intergenerational Health in Nigeria: Peripartum as Critical Life Stage for Cardiovascular Health

ENhancing Intergenerational HeAlth in Nigeria: Peripartum as Critical Life StagE for CardioVascular Health


Sponsor

Washington University School of Medicine

Enrollment

1,000 participants

Start Date

Jun 23, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of the ENHANCE-CVH study is to promote intergenerational cardiovascular health (CVH) of women and children in Abuja and the surrounding Federal Capital Territory of Nigeria. The study team plans to achieve this through an adaptation of an existing evidence based intervention - Parents as Teachers (PAT) curriculum + Healthy Eating Active Living Taught at Home (HEALTH) - among pregnant women with obesity and their children in Nigeria. The aim of the study is to evaluate the effectiveness and implementation of community health educator-led delivery of the PAT+HEALTH intervention via home visits to answer the following main questions: * Will the women participating in the intervention have a greater change in weight from baseline to 18-month follow up compared to the women who do not? * Will the women and children in the intervention group display better CVH promoting lifestyle behaviors compared to those in the control group? Participants in the study will complete baseline surveys and have clinical data, lab data, and body measurements captured. Participants will also have these procedures repeated at birth and every 6 months up to 24 months post-delivery. Once randomized to the intervention group, participants will complete 40 biweekly PAT+HEALTH curriculum delivery sessions, each lasting approximately 60-90 minutes.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a lifestyle intervention program in Nigeria to improve cardiovascular health in pregnant women who are overweight or obese. The program focuses on nutrition, physical activity, and health education to prevent heart disease risks that can develop during and after pregnancy. **You may be eligible if...** - You are 18 or older and currently pregnant at less than 14 weeks gestation - You are carrying a single baby (singleton pregnancy) - You have a BMI above 30 (obese category) - You plan to receive prenatal care and deliver at a participating health center - You are willing to take part in the program for 2 years **You may NOT be eligible if...** - You are currently enrolled in a weight loss program - You are physically unable to walk for exercise - You have an active substance use problem - You take medications known to affect weight (such as corticosteroids or antipsychotics) - You plan to relocate within the next 2 years Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALPAT+HEALTH curriculum - Nigeria

This intervention is an adaption of the PAT Curriculum and the HEALTH intervention specifically tailored for the Nigerian context.


Locations(1)

University of Abuja Teaching Hospital

Abuja, Nigeria

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NCT06773299


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