RecruitingNCT06774326

Role of Spectral CT in the Evaluation of Cardiotoxicity in Patients With Hodgkin's Lymphoma and Diffuse Large B-cell Lymphoma Treated With Anthracyclines


Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

160 participants

Start Date

Feb 14, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

To evaluate the diagnostic capability of Spectral CT (performed with contrast agent as part of routine oncological follow-up) in detecting signs of acute and chronic early-onset cardiac toxicity from anthracyclines in patients with Hodgkin's lymphoma and diffuse large B-cell lymphoma undergoing treatment regimens that include a drug from this family.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is using a new type of CT scan called Spectral CT to monitor heart health in people receiving chemotherapy (specifically anthracyclines) for Hodgkin's lymphoma or diffuse large B-cell lymphoma. Some chemotherapy drugs can damage the heart over time, and this study wants to detect that damage earlier and more accurately. **You may be eligible if...** - You are 18 years or older - You have Hodgkin's lymphoma or diffuse large B-cell lymphoma - You are receiving a chemotherapy regimen that includes anthracyclines (drugs like doxorubicin) **You may NOT be eligible if...** - You cannot receive CT contrast dye (e.g., severe kidney disease, pregnancy) - You have a history of heart disease (heart attack, heart failure, arrhythmia, cardiomyopathy, prior heart inflammation) - You have previously had radiation therapy to the chest area Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Italy

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NCT06774326


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