Development of a Radiomics Model With MR to Predict the Occurence of a Infiltration of Muscoskeletal Tumor
Development of a Radiomics Model With 3T Multiparametric MR to Predict the Occurence of a Perilesional Infiltration of Muscoskeletal Tumor During the Pre- Surgery Planning
IRCCS Azienda Ospedaliero-Universitaria di Bologna
122 participants
Mar 1, 2025
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to evaluate the feasibility and clinical utility of radiomics to diagnose peri-lesion tumour infiltration of tumours in participants with a suspect of Bone Cancer Tumor or Soft Tissue Sarcoma (STS). The main questions it aims to answer are: * is radiomics able to identify the ratio of participants truly diagnosed as positive to all those who had positive test results? * is radiomics able to identify the likelihood that a participant who has a negative test result indeed does not have the disease? Participants eligible for this study will get a MRI as part of their regular medical care. The only difference is that their data will be recorded and anonymously analyzed.
Eligibility
Inclusion Criteria4
- Age over 18
- suspect of soft tissue sarcoma with a indication for surgical treatment
- suspect of bone cancer tumor with a indication for surgical treatment
- To give informed consent
Exclusion Criteria10
- simultaneous cancer or history of cancer in the last 5 years
- acute or chronic serious conditions that could
- contraindication to conduct a Contrast-enhanced magnetic resonance imaging (MRI) such as:
- renal failure without dialysis
- history of allergy to a paramagnetic contrast agent
- claustrophobia
- symptomatic epilepsy or history of epilepsy
- cardiac pacemaker
- infusion pump, prosthesis or any implant not compatible with MRI
- pregnancy
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06774729