RecruitingNCT06774729

Development of a Radiomics Model With MR to Predict the Occurence of a Infiltration of Muscoskeletal Tumor

Development of a Radiomics Model With 3T Multiparametric MR to Predict the Occurence of a Perilesional Infiltration of Muscoskeletal Tumor During the Pre- Surgery Planning

Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

122 participants

Start Date

Mar 1, 2025

Study Type

OBSERVATIONAL

Conditions

Soft Tissue Sarcoma (STS)Bone Cancer Tumor

Summary

The goal of this observational study is to evaluate the feasibility and clinical utility of radiomics to diagnose peri-lesion tumour infiltration of tumours in participants with a suspect of Bone Cancer Tumor or Soft Tissue Sarcoma (STS). The main questions it aims to answer are: * is radiomics able to identify the ratio of participants truly diagnosed as positive to all those who had positive test results? * is radiomics able to identify the likelihood that a participant who has a negative test result indeed does not have the disease? Participants eligible for this study will get a MRI as part of their regular medical care. The only difference is that their data will be recorded and anonymously analyzed.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is developing an AI model that analyses MRI scans of soft tissue or bone tumors to predict whether the cancer has spread into surrounding tissue. This information normally requires surgery or biopsy, and a reliable scan-based prediction could help surgeons plan better. **You may be eligible if...** - You are over 18 years old - You have a suspected soft tissue sarcoma or bone tumor that needs surgery - You are able to have a contrast-enhanced MRI - You are willing to give informed consent **You may NOT be eligible if...** - You have another active cancer or had cancer within the last 5 years - You have kidney failure (without dialysis), a known allergy to MRI contrast dye, claustrophobia, epilepsy, or a cardiac pacemaker - You are pregnant - You have certain implants or devices incompatible with MRI Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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