RecruitingPhase 3NCT06775431

Comparing Prophylactic Intravenous Pethidine and Intrathecal Pethidine in Preventing Post Spinal Shivering in Caesarean Section

Comparison of Prophylactic Intravenous Pethidine Versus Intrathecal Pethidine in Preventing Post Spinal Shivering in Caesarean Section


Sponsor

Alexandria University

Enrollment

86 participants

Start Date

Dec 10, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to assess the effect of IV pethidine and intrathecal pethidine on the incidence, onset, duration, and intensity of shivering in females undergoing caesarean section. The main question it aims to answer is: which route is more efficacious in preventing shivering. Researchers will compare IV pethidine and intrathecal pethidine to see their effects on post spinal shivering, their effects on hemodynamic stability, nausea, vomiting, and sedation.


Eligibility

Sex: FEMALEMin Age: 20 YearsMax Age: 40 Years

Inclusion Criteria1

  • \-

Exclusion Criteria5

  • contraindications to spinal
  • uncontrolled hypertension, diabetes mellitus, hepatic, pulmonary diseases, and thyroid disease
  • obesity (BMI >35)
  • drug allergy
  • temperature below 36 degrees celcius or above 37.5 degrees celcius

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Interventions

DRUGPethidine Hydrochloride 50 Mg/mL Solution for Injection

Pethidine will be administered intravenously in group A 0.5 mg/kg as premedication

DRUGPethidine Hydrochloride 50 Mg/mL Solution for Injection administered intrathecally

0.2 mg/kg pethidine in trathecally will be administered with bupivacaine 0.5% in group B


Locations(1)

El-Shatby University Hospital

Alexandria, Alexandria Governorate, Egypt

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NCT06775431


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