RecruitingNCT06777628

Immunophenotype of PBMC to Early Predict Response to Immunotherapy in Hepatocellular Carcinoma

Immunophenotype of Peripheral Blood Mononuclear Cells to Early Predict Response to Immunotherapy in Hepatocellular Carcinoma


Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

100 participants

Start Date

Sep 15, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The study is aimed to test the performance of a simple, easy, reproducible cytofluorimetric assay to complement imaging studies for: * predicting response to immune-therapeutic regimens in HCC in the early phase of treatment, * to rule out pseudo-progression, * to early predict the escape from effectiveness of treatment.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • age ≥ 18 years
  • diagnosis of HCC
  • execution of laboratory tests and subsequent treatments and follow-up at our center.
  • obtained written informed consent to the study participation

Exclusion Criteria2

  • immune-related concomitant diseases
  • HIV infection

Interventions

DRUGImmunochemotherapy combined with antiangiogenic

Immunochemotherapy combined with antiangiogenic


Locations(1)

IRCCS-Azienda Ospedaliero-Universitaria di Bologna

Bologna, Laura Gramantieri, Italy

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NCT06777628


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