RecruitingNCT06780722

Study of the Occurrence of Cardiocirculatory Arrest as a Function of the Level of Hypoxemia During a Maastricht 3 Procedure

Study of the Occurrence of Cardiocirculatory Arrest as a Function of the Level of Hypoxemia During a Maastricht 3 Procedure. Prospective Observational Multicenter Study


Sponsor

Nantes University Hospital

Enrollment

50 participants

Start Date

Dec 19, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Evaluation of the level of hypoxemia during the occurrence of cardiocirculatory arrest during a Maastricht III organ donation procedure.


Eligibility

Min Age: 18 Years

Inclusion Criteria7

  • FOR THE DONORS :
  • Patient over 18 years of age
  • Organ donation procedure initiated in accordance with the legislation and procedures in force in France for the Maastricht III category
  • No opposition formulated by the relative to the patient's participation in the study
  • No opposition to the collection of data concerning him/her
  • Patient over 18 at pre-transplant consultation
  • Patient who has received an organ from a donor participating in the HEPHAISTOS protocol

Exclusion Criteria6

  • Patient registered on the national register of refusals or living refusal of donation
  • Pregnant or breast-feeding women
  • Patients under guardianship, curatorship or legal protection
  • Medical contraindication to organ donation according to the recommendations of the Agence de Biomédecine currently in force in France
  • FOR THE RECEIVER
  • \- Patients under guardianship, curatorship or legal protection

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Interventions

OTHERblood sampling

* The first sample is taken at the start of the therapeutic stop. * The second sample is taken when the mean arterial pressure drops to 45mmHg. * The third sample is taken when circulatory arrest occurs. * The fourth sample is taken at the start of extracorporeal circulation. These four samples will be destroyed at the end of the study.


Locations(12)

CHU ANGERS - Réanimation médicale

Angers, France

CH ANNECY GENEVOIS - Réanimation médicale - Coordination Prélèvements multi-organes

Annecy, France

CH AVIGNON - CH Henri Duffaut - Réanimation polyvalente

Avignon, France

CHD Vendée - Les Oudairies - Médecine Intensive Réanimation

La Roche-sur-Yon, France

CHU LILLE - Hôpital Roger Salengro - Médecine Intensive Réanimation

Lille, France

CHU de Nantes - Hôpital Laennec

Nantes, France

CHU NANTES +- Médecine Intensive Réanimation

Nantes, France

CHRU ORLEANS -Médecine Intensive Réanimation - Coordination Prélèvements multi-organes

Orléans, France

CHU POITIERS - Anesthésie Réanimation - Coordination Prélèvements multi-organes

Poitiers, France

CHU RENNES - CHU Pontchaillou - Réanimation médicale

Rennes, France

CHRU TOURS - Hôpital Bretonneau - Médecine Intensive Réanimation

Tours, France

CHBA Vannes-Auray - Réanimation Polyvalente

Vannes, France

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NCT06780722


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