RecruitingNot ApplicableNCT06784492

Incorporating Healthy Living Strategies to Aid in Recovery After Acute Pulmonary Embolism

Recovery After Acute Pulmonary Embolism


Sponsor

University of Rochester

Enrollment

100 participants

Start Date

Feb 27, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of the ERAsE-PE study is to determine whether two different healthy living strategies (along with anticoagulation) might aid in recovery after a patient is hospitalized for pulmonary embolism. Specifically, Investigators will compare changes in Cardiac Effort (#heart beats used during the 6-minute walk test/walk distance) measured after an 8-week program.


Eligibility

Min Age: 18 Years

Inclusion Criteria7

  • English speaking (>18 years old). Daily messages will be sent in English.
  • Acute PE with at least one of the following:
  • any right ventricular enlargement or dysfunction on echocardiogram;
  • CT Angiogram reporting any right ventricular enlargement; or
  • elevated cardiac biomarker (NT-pro BNP or troponin above baseline). Criteria for enrollment will be included on source document.
  • Rate controlled atrial arrythmias (resting heart rate <110 beats/m) are eligible for enrollment. This includes atrial fibrillations. This is standard of care management for atrial fibrillation.
  • Subjects do need to take prescribed anticoagulation.

Exclusion Criteria9

  • Pregnancy.
  • Cardiac Effort >3.5 beats/m during 6MWT.
  • Resting tachycardia >110 beats/m at hospital discharge.
  • Chronic Thromboembolic Pulmonary Hypertension
  • Systolic blood pressure >180 mmHg at hospital discharge.
  • Inability to walk.
  • Estimated prognosis <12 months at the time of discharge due to underlying co-morbidities (e.g., cancer).
  • Advanced neurologic disease and would not be able to comply with the messages.
  • Lack of access to email or text messaging 10. Inability or unwillingness to follow daily instructions.

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Interventions

BEHAVIORALHealthy Living Intervention-1

Participants will receive a text or email each day with instructions about a healthy intervention.

BEHAVIORALHealthy Living Intervention-2

Participants will receive a text or email each day with instructions about a healthy intervention.


Locations(1)

University of Rochester Medical Center

Rochester, New York, United States

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NCT06784492


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