RecruitingPhase 2Phase 3NCT06785337
"The Effect of Inhaled Nitroglycerin for COPD Patients
"The Effect of Inhaled Nitroglycerin on Improving Respiratory Failure in COPD Patients Admitted to Adult Intensive Care Unit"
Sponsor
Beni-Suef University
Enrollment
40 participants
Start Date
Feb 1, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
this study aims to investigative the benefits of using nebulized nitroglycerin in improving respiratory functions in patients of late stage COPD
Eligibility
Min Age: 18 Years
Inclusion Criteria1
- Adult patient's ≥ 18 years old COPD exacerbation with respiratory failure and Echo evidenced presence of pulmonary hypertension (defined as mean pulmonary artery pressure \> 20 mmHg)
Exclusion Criteria3
- Profound left ventricular failure, as the decrease in pulmonary vascular resistance results in an increase in left ventricular preload. This may worsen cardiogenic pulmonary edema.
- Pregnant female patients
- Patient with hypersensitivity to nitroglycerin
Interventions
DRUGInhaled nitroglycerin
Inhaled nitroglycerin
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06785337
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