RecruitingNCT06788639

A Study of Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Treated With Lisocabtagene Maraleucel in the Post-Marketing Setting

Non-interventional Cohort Study of Patients Treated With Liso-cel (Lisocabtagene Maraleucel) for Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in the Post-Marketing Setting


Sponsor

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Enrollment

300 participants

Start Date

Feb 4, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to characterize the long-term safety of lisocabtagene maraleucel (liso-cel), focusing on patients treated in the chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) indication, and will be part of post-marketing liso-cel pharmacovigilance activities


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is collecting real-world data on patients with a type of blood cancer called chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who received a CAR-T cell therapy called lisocabtagene maraleucel (also known as liso-cel) after it became commercially available. CAR-T therapy uses a patient's own immune cells, which are modified in a lab to attack cancer. The study aims to understand how this treatment performs outside of clinical trial settings. **You may be eligible if...** - You have relapsed or refractory CLL or SLL (cancer that came back or stopped responding to treatment) - You received at least one infusion of liso-cel as a commercially approved treatment in the United States - Your treatment followed the approved prescribing guidelines **You may NOT be eligible if...** - You were participating in another investigational study at the time you received liso-cel - The CAR-T cell product you received did not meet commercial quality specifications Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALLisocabtagene maraleucel

According to the United States Prescribing Information


Locations(1)

Center for International Blood and Marrow Transplant Research (CIBMTR)

Milwaukee, Wisconsin, United States

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NCT06788639


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