The Diagnostic Accuracy and Clinical Value of FAPI PET in Pleural Mesothelioma

This study is evaluating a new type of PET scan (a detailed imaging test) called FAPI PET to see how accurately it can detect and stage pleural mesothelioma — a rare cancer of the lining around the lungs often associated with asbestos exposure. The study compares FAPI PET to the current standard scan (FDG PET/CT) to see if it provides better information for diagnosis and treatment planning. **You may be eligible if...** - You are 18 years or older - You have suspicious lesions in the lining of the lung (pleura) being investigated for possible mesothelioma - You have been referred for a pleural biopsy (tissue sample) - You have already had or are scheduled to have a standard FDG PET/CT scan as part of your workup - You are physically and mentally capable of participating **You may NOT be eligible if...** - You need urgent surgery - You have another active cancer being treated within the past year - You are pregnant, breastfeeding, or could potentially be pregnant Talk to your doctor to see if this trial is right for you.