RecruitingNCT06790836

Correlation of FFR CT With Invasive FFR in Multi-ethnic Cohort- a Retrospective Study

Correlation of Fractional Flow Reserve Computed Tomography (FFR CT) Findings With Invasive FFR in Coronary Artery Disease (CAD) in a Multi-ethnic Cohort- a Retrospective Study


Sponsor

Sandwell & West Birmingham Hospitals NHS Trust

Enrollment

500 participants

Start Date

May 1, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to examine the correlation between Fractional Flow Reserve (FFR) FFR Computed Tomography (CT) and invasive FFR in a real-world setting using retrospective analysis of existing data, providing practical insights directly applicable to patient care. By confirming or examining the accuracy of FFR CT in a clinical setting, our analysis could support its broader adoption as a routine non-invasive diagnostic tool potentially (a) reducing the need for invasive testing (b) minimising associated risks, and(c) lowering healthcare costs and provide fresh insights into non-invasive coronary diagnostics. Our findings will also help understand the relevance of these tests across different ethnic groups and the population we serve.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • ≥18 years
  • Stable •patients with suspected CAD
  • Patients who underwent CTCA, FFR CT and had an invasive FFR.
  • CTCA images of high-quality for analysis, with clear visualisation of coronary arteries and minimal artifacts.

Exclusion Criteria3

  • <18 years of age
  • Did not undergo FFR CT
  • Inadequate quality/degraded CTCA images

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Locations(1)

Sandwell and West Birmingham NHS Trust

Birmingham, West Midlands, United Kingdom

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NCT06790836


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