Correlation of FFR CT With Invasive FFR in Multi-ethnic Cohort- a Retrospective Study
Correlation of Fractional Flow Reserve Computed Tomography (FFR CT) Findings With Invasive FFR in Coronary Artery Disease (CAD) in a Multi-ethnic Cohort- a Retrospective Study
Sandwell & West Birmingham Hospitals NHS Trust
500 participants
May 1, 2026
OBSERVATIONAL
Conditions
Summary
This study aims to examine the correlation between Fractional Flow Reserve (FFR) FFR Computed Tomography (CT) and invasive FFR in a real-world setting using retrospective analysis of existing data, providing practical insights directly applicable to patient care. By confirming or examining the accuracy of FFR CT in a clinical setting, our analysis could support its broader adoption as a routine non-invasive diagnostic tool potentially (a) reducing the need for invasive testing (b) minimising associated risks, and(c) lowering healthcare costs and provide fresh insights into non-invasive coronary diagnostics. Our findings will also help understand the relevance of these tests across different ethnic groups and the population we serve.
Eligibility
Inclusion Criteria4
- ≥18 years
- Stable •patients with suspected CAD
- Patients who underwent CTCA, FFR CT and had an invasive FFR.
- CTCA images of high-quality for analysis, with clear visualisation of coronary arteries and minimal artifacts.
Exclusion Criteria3
- <18 years of age
- Did not undergo FFR CT
- Inadequate quality/degraded CTCA images
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Locations(1)
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NCT06790836