RecruitingNCT06793085

Pro- and Anti-inflammatory Cytokines in PCOS

Assessment of the Concentrations of Pro- and Anti-inflammatory Cytokines and Their Association With the Metabolic Profile of Women With PCOS

Sponsor

Jagiellonian University

Enrollment

100 participants

Start Date

Jan 20, 2025

Study Type

OBSERVATIONAL

Conditions

Reproductive Age PCOS (Polycystic Ovary Syndrome)

Summary

The study will involve measurements and comparisons of the concentrations of pro-inflammatory cytokines: IL-6, TNF-α, IL-18, as well as anti-inflammatory cytokine IL-4 in women with polycystic ovary syndrome (PCOS) and insulin resistance, women with polycystic ovary syndrome without carbohydrate metabolism disorders, and women without PCOS (control group).

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This study measures levels of inflammatory proteins in the blood of women with polycystic ovary syndrome (PCOS) to better understand how inflammation may play a role in this condition, which can cause irregular periods, excess hormones, and fertility problems. **You may be eligible if...** - You are a woman between 18 and 45 years old **You may NOT be eligible if...** - You have had at least one ovary surgically removed - You have treated diabetes - You have a diagnosed and treated metabolic, autoimmune, or inflammatory disease Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTMeasurement of interleukin-6 (il-6) concentration in blood serum

Measurement of fasting interleukin-6 (il-6) concentration in fasting venous blood serum

DIAGNOSTIC_TESTMeasurement of fasting tumor necrosis factor α (TNF-α) concentration

Measurement of fasting tumor necrosis factor α concentration in fasting venous blood serum

DIAGNOSTIC_TESTMeasurement of interleukin-18 (il-18) concentration

Measurement of interleukin-18 (il-18) concentration in fasting venous blood serum

DIAGNOSTIC_TESTMeasurement of interleukin-4 (il-4) concentration

Measurement of interleukin-4 (il-4) concentration in fasting venous blood plasma

Locations(1)

Jagiellonian University

Krakow, Poland

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NCT06793085

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