Pro- and Anti-inflammatory Cytokines in PCOS
Assessment of the Concentrations of Pro- and Anti-inflammatory Cytokines and Their Association With the Metabolic Profile of Women With PCOS
Jagiellonian University
100 participants
Jan 20, 2025
OBSERVATIONAL
Conditions
Summary
The study will involve measurements and comparisons of the concentrations of pro-inflammatory cytokines: IL-6, TNF-α, IL-18, as well as anti-inflammatory cytokine IL-4 in women with polycystic ovary syndrome (PCOS) and insulin resistance, women with polycystic ovary syndrome without carbohydrate metabolism disorders, and women without PCOS (control group).
Eligibility
Inclusion Criteria1
- women aged 18-45 years
Exclusion Criteria5
- previous removal of at least one ovary
- treated diabetes of any type
- diagnosed and treated metabolic diseases
- diagnosed and treated autoimmune diseases
- diagnosed and treated autoinflammatory diseases
Interventions
Measurement of fasting interleukin-6 (il-6) concentration in fasting venous blood serum
Measurement of fasting tumor necrosis factor α concentration in fasting venous blood serum
Measurement of interleukin-18 (il-18) concentration in fasting venous blood serum
Measurement of interleukin-4 (il-4) concentration in fasting venous blood plasma
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06793085