RecruitingNot ApplicableNCT07571915

Health-Related Quality of Life and Metabolic Outcomes in PCOS

Health-Related Quality of Life and Metabolic Outcomes in PCOS: A Feasibility Study of Comprehensive PCOS Education and Lifestyle Modification Support Delivered Via Synchronous Virtual Groups

Sponsor

The Cleveland Clinic

Enrollment

40 participants

Start Date

May 23, 2026

Study Type

INTERVENTIONAL

Conditions

PCOS (Polycystic Ovary Syndrome)

Summary

The primary outcome of interest is change in PCOS health-related quality of life, while the secondary outcome of interest is change in adiposity, cardiometabolic, and inflammation biomarkers.

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 49 Years

Inclusion Criteria2

Non-pregnant females ages 18-49 years
Preexisting diagnoses of PCOS and obesity (body-mass index (BMI) equal or greater to 30 kg/m2) at enrollment

Exclusion Criteria9

Patients who are pregnant or planning to become pregnant during the study period
Patients currently or with recent participation (< 12 months at the time of enrollment) in a PCOS-focused group
Patients with documented monogenic obesity
Patients with a diagnosis of any type of diabetes (with the exclusion of prediabetes)
Patients on systemic glucocorticoid therapy > 7 days at the time of enrollment
Patients with any end-stage organ disease
Patients without access to internet
Patients requiring English language interpretation
Any condition which, based on the investigator's medical judgment, would preclude patient ability to complete the study