RecruitingNCT06795386

Chronic Widespread Pain After Rapid Weight Loss in Non-Hispanic Black and Hispanic/Latino/a/x Adults

Determining Mechanisms of Pain Reduction in Chronic Widespread Pain After Rapid Weight Loss in Non-Hispanic Black and Hispanic/Latino/a/x Adults


Sponsor

New York University

Enrollment

60 participants

Start Date

Oct 9, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to learn if surgical weight loss can improve chronic widespread pain in people living with higher BMI who self-identify as Hispanic/Latino ethnicity or non-Hispanic Black based on the United States census racial categories. The main questions the study aims to answer are: 1. Do pain at rest (primary outcome) and movement-evoked pain (secondary outcome) improve after bariatric surgery? 2. Do pain processing and joint function change after bariatric surgery? 3. Are pain processing and joint function associated with clinically significant pain change after surgical weight loss? Researchers will compare pain and function before and 6 months after bariatric surgery in a single cohort.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This observational study is examining whether bariatric (weight loss) surgery improves chronic widespread pain — persistent pain in multiple body areas — in Hispanic/Latino and non-Hispanic Black adults who are eligible for bariatric surgery, as these communities are underrepresented in pain and surgical research. Researchers will assess pain at rest, movement-evoked pain, pain processing, and joint function before surgery and again 6 months later to see how much improvement occurs. Adults who self-identify as Black/African American or Hispanic/Latino, have a BMI of 40 or higher (or 35+ with a health comorbidity), experience chronic widespread pain (pain in 3+ body areas on both sides of the body, rated 3/10 or higher), and can walk independently are eligible — those with prior bariatric surgery or autoimmune conditions are excluded. Participation involves two in-person lab visits (before and 6 months after surgery) plus one remote visit at 3 months for questionnaires and pain assessments, with no changes to the planned surgical procedure. This summary was prepared with AI assistance to help patients understand the study in plain language.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBariatric Surgery

Participants will include people with chronic widespread pain who will undergo bariatric surgery. All participants will receive this intervention and will not be randomized to this or other interventions.


Locations(3)

NYU Steinhardt Arthur J. Nelson Laboratory

New York, New York, United States

New York City Health + Hospitals/Bellevue Hospital

New York, New York, United States

NYU CTSI Clinical Research Center

New York, New York, United States

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NCT06795386


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