Left Atrial Posterior Wall and Mitral Isthmus PF Ablation in Non-Paroxysmal AF Patients

This study is comparing two approaches for treating persistent atrial fibrillation (an irregular heartbeat that doesn't stop on its own) using catheter ablation — a procedure that uses energy to create scar tissue in the heart to block abnormal electrical signals. **You may be eligible if...** - You have non-paroxysmal (persistent or long-standing) atrial fibrillation - Your doctor has recommended catheter ablation per current guidelines - You are willing to sign an informed consent form **You may NOT be eligible if...** - You have a blood disorder associated with spontaneous red blood cell breakdown - You have moderate to severe chronic kidney disease (stage 3 or worse) - You have previously had a left atrial ablation procedure Talk to your doctor to see if this trial is right for you.