Adrenaline Nasal Pack vs Xylometazoline Nasal Drops During Nasotracheal Intubation
Comparison of the Efficacy of Adrenaline Nasal Pack and Xylometazoline Nasal Drops in Decreasing Nasal Bleeding During Nasotracheal Intubation
Shaheed Mohtarma Benazir Bhutto Institue of Trauma
70 participants
Dec 1, 2024
INTERVENTIONAL
Conditions
Summary
The goal of this trial is to compare efficacy of xylometazoline nasal drops and adrenaline nasal pack in participants undergoing elective oromaxillofacial surgeries. The main question aim to answer is xylometazoline nasal drops better than adrenaline nasal packing in terms of nasal bleeding during nasotracheal intubation. Researchers are comparing 2 groups of participants. Participants in group Xylometazoline are receiving 0.1% xylometaxoline nasal drops. Participants in group Adrenaline are receiving adrenaline nasal packing.
Eligibility
Inclusion Criteria5
- ASA 1 and 2
- Age group between 18-60 years
- Mallampati score 1 and 2
- Either gender
- Participants who undergo elective oromaxillofacial surgery
Exclusion Criteria6
- Lack of consent
- Participants with anticipated difficult airway
- Participants receiving anticoagulant therapy
- History of nasal abnormality (nasal surgery, trauma, polyp, obstruction)
- History of repeated epistaxis
- History of uncontrolled hypertension, diabetes, pregnancy, and any other cardiac or cerebral events.
Interventions
Xylometazoline is direct acting, non selective, adrenergic agonist binding with alpha 1\&2 receptors, used for vasoconstriction to decrease nasal bleeding.
Adrenaline is direct acting, non selective, adrenergic agonist binding with alpha and beta receptors both, used for vasoconstriction to decrease nasal bleeding.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06801522