Efficacy of Individualized Aerobic Exercise Training in Patients With Inflammatory Bowel Disease
Telemedicine-based Individualized Aerobic Exercise Training in Adults With Inactive or Mildly Active Inflammatory Bowel Disease: A Semi-crossover Randomized Controlled Trial
Ningbo Medical Center Lihuili Hospital
28 participants
May 1, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to learn if a 12-week individualized aerobic training program helps manage inactive or mildly active inflammatory bowel disease (IBD) including Crohn's disease (CD) and ulcerative colitis (UC) in adult patients aged 18-65 years. It will also assess participant compliance and the safety of the training program. The main questions it aims to answer are: 1. Does this aerobic training program improve the cardiopulmonary function of participants? 2. Does this aerobic training program help control disease activity? 3. Does this aerobic training program improve participants' quality of life? Researchers will divide participants into two groups. One group will participate in the training program directly. The other group will first undergo a 12-week control intervention (i.e., standard treatment) before proceeding to the training program. Participants will: 1. Take part in the individualized aerobic training program according to their baseline physical activity level for 12 weeks. 2. Visit the clinic once every 4 weeks for check-ups and tests. 3. Keep a diary of symptoms.
Eligibility
Inclusion Criteria4
- Diagnosed with CD or UC for more than 3 months.
- Disease activity in remission or mildly active (CD: CDAI < 220; UC: pMS < 5).
- Baseline physical activity intensity is low, measured by the IPAQ Chinese version short form, and without a habit of "regular exercise".
- Agree to participate in the study and accept a 12-week individualized aerobic exercise training program.
Exclusion Criteria4
- Pregnant or breastfeeding, or planning to become pregnant within the next 3 months.
- Presence of physical movement disorders or other chronic diseases that limit physical activity.
- Having an ileostomy.
- History of anal or intestinal surgery within the past 3 months.
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Interventions
After enrollment, subjects directly participate in a 12-week aerobic exercise training program. The training plan provides individualized progressive aerobic training based on their baseline physical activity level measured by International Physical Activity Questionnaire (IPAQ), with the exercise intensity being increased every four weeks.
After enrollment, subjects first undergo a 12-week control intervention (i.e., routine treatment) and then participate in a 12-week aerobic exercise training program. The training plan provides individualized progressive aerobic training based on their baseline physical activity level IPAQ, with the exercise intensity being increased every four weeks.
Locations(1)
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NCT06804733