RecruitingNCT07237516

Zymfentra (Infliximab-dyyb) REal World Cohort STudy


Sponsor

University of North Carolina, Chapel Hill

Enrollment

200 participants

Start Date

Nov 20, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to learn about how effective Zymfentra (IFX=dyyb) is when treating patients with Crohn's disease (CD) and ulcerative colitis (UC) Does Zymfentra lead to a reduction in symptoms at intervals throughout one year? Participants being prescribed Zymfentra (IFX-dyyb as part of their regular medical care for CD or UC will answer online survey questions about their bowel habits for 1 year.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This real-world observational study is following people with inflammatory bowel disease (Crohn's disease, ulcerative colitis, or related conditions) who are switching to or starting a new form of infliximab (a biologic medication) called Zymfentra, which is given as an injection under the skin rather than by IV infusion. **You may be eligible if...** - You are 18 or older - You have been diagnosed with Crohn's disease, ulcerative colitis, or inflammatory bowel disease unclassified - You are starting Zymfentra (subcutaneous infliximab-dyyb) at week 10 after IV induction therapy, OR you are switching from IV infliximab to Zymfentra during maintenance - You are expected to be followed at the participating clinic for at least 12 months **You may NOT be eligible if...** - You do not have a confirmed IBD diagnosis - You are unwilling to be followed up for the study period Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(5)

University of Iowa

Iowa City, Iowa, United States

Mercy Medical Center

Baltimore, Maryland, United States

Brigham and Women's Hospital

Boston, Massachusetts, United States

New York University

New York, New York, United States

University of North Carolina

Chapel Hill, North Carolina, United States

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NCT07237516


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