RecruitingPhase 1Phase 2NCT06809998

COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty

COSTI: COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty - A Triple Blinded, Randomized Controlled Trial Pilot Study

Sponsor

Unity Health Toronto

Enrollment

60 participants

Start Date

Jan 24, 2025

Study Type

INTERVENTIONAL

Conditions

Total Knee Anthroplasty Osteoarthritis Primary Bilateral Knee Osteoarthritis Osteoarthritis(OA) of the knee

Summary

Through a triple-blinded randomized control trial, the primary purpose of this pilot study is to assess the efficacy of administering peri-operative contralateral corticosteroid injection in patients undergoing TKA. The secondary outcome was to assess the effect of contralateral corticosteroid injection on pain and functional outcomes of patients undergoing TKA.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Band-Aid and a drug called Corticosteroid Injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL). for people with bilateral knee osteoarthritis, osteoarthritis primary, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCorticosteroid Injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL).

Corticosteroid Injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL).

OTHERBand-Aid

Band-Aid

Locations(1)

St. Michael's Hospital

Toronto, Ontario, Canada

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NCT06809998

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