RecruitingPhase 3NCT06810375

Erector Spinae Versus Intercostal Nerve Blocks With Liposomal Bupivacaine for Analgesia in Thoracic Surgery


Sponsor

George Washington University

Enrollment

120 participants

Start Date

Mar 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial compares efficacy in postoperative pain management in thoracic surgery between erector spinae block versus liposomal bupivacaine injections.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two types of nerve block injections used to manage pain after chest surgery: an erector spinae block (injected along the back muscles near the spine) versus an intercostal nerve block (injected between the ribs). Both use a long-acting local anesthetic called liposomal bupivacaine. **You may be eligible if...** - You are scheduled to have chest (thoracic) surgery - You are an adult who can consent to participate - You meet the general health requirements for elective surgery **You may NOT be eligible if...** - You have allergies to local anesthetic medications - You are pregnant or breastfeeding - You have bleeding disorders or take blood thinners that make nerve blocks unsafe - You have had prior surgery or anatomy changes in the relevant area Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGErector Spinae (ESP) Block with Bupivacaine (Marcaine®)

preoperative erector spinae block with bupivacaine (Marcaine®)

DRUGIntercostal nerve block

intraoperative intercostal nerve block with liposomal bupivacaine (Exparel®)


Locations(1)

The George Washington University Hospital

Washington D.C., District of Columbia, United States

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NCT06810375


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