RecruitingPhase 2Phase 3NCT06815237

Effects of Ketone Supplement and Alcohol on Brain Metabolism

Acute Effects of Ketone Supplementation and Alcohol on Brain Metabolism


Sponsor

University of Pennsylvania

Enrollment

60 participants

Start Date

May 13, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The research study is being conducted to better understand the effects of ketones and alcohol on brain functioning and brain metabolism. Participants will be asked to undergo three identical MRI visits after three single-dose interventions: (1) drink a ketone supplement drink, (2) drink an alcoholic beverage, (3) no intervention. These interventions will be randomly assigned (meaning everyone receives all 3 interventions, but in different orders).


Eligibility

Min Age: 21 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Alcohol beverage and Kenetik for people with alcohol drinking, ketosis, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 21 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTKenetik

Ketone supplement is randomly given once.

OTHERAlcohol beverage

Alcohol beverage is randomly given once. Participants will receive the alcohol beverage that dose-adjusts for body weight and sex differences in pharmacokinetics and calculated to obtain a final breath alcohol concentration of 0.050%


Locations(1)

Center for Studies of Addiction

Philadelphia, Pennsylvania, United States

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NCT06815237


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