RecruitingNot ApplicableNCT06815302

TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD

TURN-IT FOG: A Novel Intervention to Improve Turning in People With PD and Freezing of Gait


Sponsor

Oregon Health and Science University

Enrollment

60 participants

Start Date

Jun 2, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkinson's disease, as assessed by patients, clinicians, and wearable sensors, and 2) to explore whether two different rehabilitation intervention can reduce FOG and improve daily life mobility in people with FOG sufficiently to justify a clinical trial. Participants will: * Be randomly assigned to one of two intervention groups (turning-focused agility exercise or strength-based exercise) * Have one-on-one training sessions three times per week for 6 weeks * Perform in-lab assessments before beginning and after completing the study intervention * Use wearable mobility sensors during daily life to measure their walking and balance


Eligibility

Min Age: 50 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is testing an exercise-based program called TURN-IT FOG to help people with Parkinson's disease who experience "freezing of gait" — episodes where the feet suddenly feel stuck to the ground while walking or turning. This is a dangerous symptom that increases fall risk. The 6-week program includes specially designed exercises targeting turning movements to reduce freezing episodes. **You may be eligible if...** - You are between 50 and 80 years old - You have been diagnosed with Parkinson's disease by a movement disorder neurologist - You experience freezing of gait (as measured by a standard questionnaire) - You are in Hoehn and Yahr stage II–IV (moderate Parkinson's) - You are able to exercise 3 times a week for 6 weeks **You may NOT be eligible if...** - You have a major bone, joint, or other neurological condition significantly affecting walking - You have epilepsy or an acute illness - Your physical or cognitive condition prevents you from safely participating Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALExperimental intervention

Specific participant procedures in experimental and active control interventions are simplified to preserve study blinding.

BEHAVIORALActive intervention

Specific participant procedures in experimental and active control interventions are simplified to preserve study blinding.


Locations(3)

Arizona State University

Tempe, Arizona, United States

Oregon Health and Science University

Portland, Oregon, United States

University of São Paulo, Bauru Campus

Bauru, São Paulo, Brazil

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NCT06815302


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