RecruitingNCT06817408

Dynamics of Organ Damage and Immune Exhaustion During Sepsis

Cell-free DNA Epigenomics to Track the Dynamics of Organ Damage and Immune Exhaustion During Sepsis


Sponsor

Mayo Clinic

Enrollment

1,000 participants

Start Date

Mar 25, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This is a prospective, non-randomized study investigating if organ damage and immune changes can be measured by liquid biopsy NGS through advanced analytical methods.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • • Patients who've developed a shocked state (Hypotension or Lactate grade \>4) or Clinical Concern

Exclusion Criteria3

  • \<18 years of age
  • Pregnant Women
  • Nursing women

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Interventions

OTHERObservation

One additional blood draw in the Emergency Department as part of their standard of care visit.


Locations(1)

Mayo Clinic Rochester

Rochester, Minnesota, United States

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NCT06817408


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